Detailed information NTG0729299

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: N4G38_RS11160
• Genome accession: NZ_CP104386
• Coordinates: 2378173..2380686 (-)
• Length: 837 a.a.
• NCBI ID: WP_252252802.1
• Uniprot ID: -
• Organism: Cupriavidus gilardii strain WM02
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	2378173..2389088	2378173..2380686	within	0

Gene organization within MGE regions

Location: 2378173..2389088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N4G38_RS11160 (N4G38_11160)	comA	2378173..2380686 (-)	2514	WP_252252802.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
N4G38_RS11165 (N4G38_11165)	-	2380867..2381709 (-)	843	WP_260730457.1	TatD family hydrolase	-
N4G38_RS11170 (N4G38_11170)	lolD	2381737..2382489 (-)	753	WP_260730458.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
N4G38_RS11175 (N4G38_11175)	-	2382482..2383732 (-)	1251	WP_053821509.1	lipoprotein-releasing ABC transporter permease subunit	-
N4G38_RS11180 (N4G38_11180)	-	2383861..2385012 (+)	1152	WP_053823045.1	hypothetical protein	-
N4G38_RS11185 (N4G38_11185)	recJ	2385104..2386801 (+)	1698	WP_053821508.1	single-stranded-DNA-specific exonuclease RecJ	-
N4G38_RS11190 (N4G38_11190)	-	2386913..2387659 (-)	747	WP_151023243.1	M23 family metallopeptidase	-
N4G38_RS11195 (N4G38_11195)	prfB	2387984..2389088 (+)	1105	WP_260730459.1	peptide chain release factor 2	-

Sequence

Protein

• Length: 837 a.a.
• Molecular weight: 88991.76 Da
• Isoelectric Point: 11.6881

>NTDB_id=729299 N4G38_RS11160 WP_252252802.1 2378173..2380686(-) (comA) [Cupriavidus gilardii strain WM02]
MRLTLCAFVAGCWLVQQLPALPPASIGVTAGLAALVVVIALSPLAGRPGPSSIGLHVRLLATVLAALIVGAAWSVWRAER
RLAERLAAQFEGVTLSLTGVVSGLPTGNGEGLRFAFTVDGDRPAGLPPLLSLGWQQAPPDLLPGTRLAVTARLKRPHGLA
NPHGFDYEYWLLQRGIGATGYVLAARPAAPVALRPAWRIARWRAQIRSRMLAAMPAEAPLAGVLVALAIGDQSGIAAEQW
RWFTRTGIGHLVSISGLHITMISGLAGALARALWRRSFGVGRWLRRPLPLRCPAQRAAALVAVAMALGYGLLSGMEVPAQ
RTVAMVSVAALALWWQRRPPASLVLAWAAAVALALDPWAVRAAGFWLSFGAVAAIFVAASQRTVAVTGGEPSQRSVWQAR
WQGVRRHLAESVRTQWAVTIGLLPPTLLLFQQVSVVSPLANALAIPLVSLLVTPLALCAALLAAWPVDWPAGGAIAMAAA
SLLALAHQAMAWLAAALVRLAAPDWAVWQAARPDTVELAFALLGTAVLLAPRAFGWGWRVHGLVLLIPMLSSGRAPLPAA
AFRATALDVGQGAAVLIETRGHRLLYDAGPAYGPADAPRPSAGERVVVPFLRAVGIHSLDALVISHEDADHAGGARDVMA
ALPVRRLWGSLPRGHPLWRWPPGGGPDVGQVCAAGIAWQWDGVRFELLHPLPGQGDDAAIGSNARSCVLRVSSPYAAMLL
TGDIDRAAELAMVARLPPDALRADLLLVPHHGSRTSSSDEWLDAVRPAAAVFQLGYRNRYRHPHAQVWARYGRRGIARYR
SDRTGAVEVVADRDGIAIASFRQQARRYWRPAPDAPE

Nucleotide

• Length: 2514 bp

>NTDB_id=729299 N4G38_RS11160 WP_252252802.1 2378173..2380686(-) (comA) [Cupriavidus gilardii strain WM02]
ATGCGCCTGACGCTGTGCGCCTTCGTCGCGGGCTGCTGGCTGGTGCAGCAATTGCCGGCATTGCCGCCAGCGTCGATCGG
CGTGACCGCCGGTCTGGCCGCATTGGTCGTGGTGATCGCGCTGTCGCCGCTTGCCGGGCGTCCGGGGCCTTCCTCGATCG
GCCTCCATGTGCGCTTGCTGGCCACCGTGCTGGCCGCGCTGATCGTCGGCGCGGCATGGTCCGTCTGGCGTGCCGAGCGT
CGCCTGGCCGAGCGGCTTGCGGCGCAGTTCGAAGGCGTCACGCTGTCGCTGACGGGCGTGGTGTCGGGACTGCCGACGGG
CAACGGCGAGGGCCTGCGTTTCGCGTTCACGGTCGACGGCGACAGGCCGGCCGGCTTGCCGCCGCTGCTGTCGCTCGGCT
GGCAGCAGGCGCCGCCCGATCTGCTGCCCGGCACGCGGCTGGCGGTGACCGCACGGCTGAAGCGGCCACATGGTCTCGCC
AATCCGCATGGCTTCGACTACGAATACTGGCTGCTGCAGCGGGGCATTGGCGCAACCGGCTACGTGCTGGCGGCCCGCCC
CGCAGCGCCGGTGGCCCTGCGGCCGGCCTGGCGCATTGCCCGCTGGCGTGCGCAGATCCGGTCCCGCATGCTGGCGGCGA
TGCCGGCCGAGGCGCCGTTGGCGGGCGTGCTGGTGGCGCTGGCGATCGGCGACCAGAGCGGCATCGCCGCCGAGCAGTGG
CGCTGGTTCACGCGCACCGGCATCGGCCATCTGGTCAGCATCTCGGGCCTGCATATCACGATGATCTCGGGGCTGGCGGG
CGCGCTGGCACGGGCCCTGTGGCGGCGCTCGTTCGGCGTGGGCAGATGGCTGCGGCGGCCGCTGCCGTTGCGTTGTCCGG
CGCAGCGGGCGGCGGCGCTGGTCGCCGTGGCGATGGCGCTCGGCTATGGGCTGCTGTCGGGTATGGAGGTGCCGGCGCAA
CGCACGGTGGCGATGGTATCCGTGGCCGCGCTGGCGCTGTGGTGGCAGCGCCGGCCGCCGGCCTCGCTGGTGCTGGCCTG
GGCCGCCGCGGTCGCGCTGGCGCTCGACCCGTGGGCGGTGCGGGCGGCGGGCTTCTGGCTGTCGTTCGGCGCGGTCGCCG
CGATCTTCGTGGCGGCGTCGCAGCGAACCGTGGCCGTGACCGGCGGCGAGCCGTCGCAGCGTTCGGTCTGGCAGGCGCGC
TGGCAAGGCGTGCGGCGGCACCTGGCCGAGTCGGTGCGCACGCAATGGGCCGTCACGATCGGACTGCTGCCGCCGACGCT
GCTGTTGTTCCAGCAGGTGTCGGTGGTGTCGCCGCTGGCCAATGCGCTGGCGATTCCGCTCGTCAGCCTGCTGGTGACGC
CGCTGGCGTTGTGCGCGGCGCTGCTGGCCGCCTGGCCCGTGGACTGGCCGGCAGGCGGCGCCATCGCGATGGCGGCCGCA
TCGCTGCTGGCGCTGGCGCACCAGGCGATGGCATGGCTGGCGGCGGCGCTGGTGCGGCTGGCGGCGCCGGACTGGGCCGT
CTGGCAGGCGGCGCGGCCGGACACGGTCGAGCTCGCCTTCGCGCTGCTCGGCACGGCGGTGCTGCTGGCCCCGCGCGCCT
TCGGCTGGGGCTGGCGCGTGCACGGCCTGGTGCTGCTGATCCCGATGCTGTCGAGCGGCCGCGCGCCGCTGCCGGCCGCG
GCCTTCCGCGCGACGGCGCTCGATGTCGGACAGGGCGCGGCGGTGCTGATCGAGACCCGCGGCCATCGCCTGCTGTACGA
CGCCGGGCCAGCCTATGGCCCCGCCGACGCGCCACGGCCCAGCGCCGGCGAACGCGTGGTGGTGCCGTTCCTGCGCGCGG
TCGGCATCCATTCGCTCGATGCGCTGGTGATCAGCCACGAGGATGCCGATCATGCCGGCGGTGCGCGCGACGTGATGGCC
GCGCTGCCGGTCCGGCGCCTGTGGGGCTCGCTGCCGCGTGGCCATCCGCTATGGCGGTGGCCGCCCGGGGGCGGACCCGA
TGTCGGTCAGGTGTGCGCGGCCGGTATCGCGTGGCAATGGGACGGCGTGCGTTTCGAACTGCTGCATCCGTTGCCGGGGC
AGGGCGACGACGCGGCGATCGGCAGCAATGCGCGCAGCTGCGTGCTGCGGGTCTCGAGTCCTTACGCCGCGATGCTGCTG
ACCGGCGATATCGACCGCGCCGCCGAACTGGCGATGGTGGCGCGCCTGCCGCCCGATGCGCTGCGCGCCGACCTGCTGCT
GGTGCCGCACCATGGCAGCCGCACCTCGTCCAGCGACGAATGGCTCGACGCGGTAAGGCCCGCCGCGGCGGTGTTCCAGC
TCGGCTATCGCAACCGCTACCGGCATCCGCATGCGCAGGTATGGGCGCGCTATGGCCGCCGCGGGATCGCGCGCTATCGC
AGCGATCGCACCGGCGCGGTCGAAGTCGTCGCGGATCGGGACGGCATCGCGATCGCGTCGTTCCGGCAGCAGGCGCGGCG
CTACTGGCGGCCGGCGCCGGATGCGCCGGAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (227-530)

• Domain of unknown function (DUF4131) (DUF4131) (20-183)

• Metallo-beta-lactamase superfamily (Lactamase_B) (568-771)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Ralstonia pseudosolanacearum GMI1000	48.492	100	0.499