Detailed information NTG0072835

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GDK20_RS14760
• Genome accession: NZ_AP019545
• Coordinates: 2859435..2860322 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain KG-22
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2854435..2865322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GDK20_RS14725	-	2854454..2854546 (+)	93	WP_010956583.1	hypothetical protein	-
GDK20_RS14730 (SAKG22_27060)	-	2854654..2855151 (-)	498	WP_001065268.1	glutathione peroxidase	-
GDK20_RS14735 (SAKG22_27070)	-	2855161..2855421 (-)	261	WP_001791974.1	hypothetical protein	-
GDK20_RS14745	-	2855803..2855916 (-)	114	Protein_2809	hypothetical protein	-
GDK20_RS14750 (SAKG22_27080)	-	2856575..2858575 (-)	2001	WP_000776751.1	ABC transporter permease	-
GDK20_RS14755 (SAKG22_27090)	-	2858572..2859327 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
GDK20_RS14760 (SAKG22_27100)	braS	2859435..2860322 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GDK20_RS14765 (SAKG22_27110)	braR	2860333..2860998 (-)	666	WP_152064787.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GDK20_RS14770 (SAKG22_27120)	-	2861024..2861224 (-)	201	WP_000604730.1	hypothetical protein	-
GDK20_RS14775 (SAKG22_27130)	-	2861422..2862846 (+)	1425	WP_000953755.1	alkaline phosphatase	-
GDK20_RS15355	-	2862916..2863026 (+)	111	Protein_2816	hypothetical protein	-
GDK20_RS14785 (SAKG22_27150)	-	2863129..2863584 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GDK20_RS14790 (SAKG22_27160)	-	2863829..2864590 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=72835 GDK20_RS14760 WP_000143425.1 2859435..2860322(-) (braS) [Staphylococcus aureus strain KG-22]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=72835 GDK20_RS14760 WP_000143425.1 2859435..2860322(-) (braS) [Staphylococcus aureus strain KG-22]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1