Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | GDK20_RS00315 | Genome accession | NZ_AP019545 |
| Coordinates | 64273..65901 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain KG-22 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 45907..67272 | 64273..65901 | within | 0 |
| ICE | 59052..104109 | 64273..65901 | within | 0 |
Gene organization within MGE regions
Location: 45907..104109
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GDK20_RS00205 (SAKG22_00400) | mecA | 45907..47916 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| GDK20_RS00210 (SAKG22_00410) | mecR1 | 48013..49770 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| GDK20_RS00215 (SAKG22_00420) | mecI | 49770..50141 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| GDK20_RS00220 | psm-mec | 50226..50294 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| GDK20_RS00225 (SAKG22_00430) | - | 50628..51758 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| GDK20_RS00230 (SAKG22_00450) | cstB | 51872..53206 (-) | 1335 | Protein_41 | persulfide dioxygenase-sulfurtransferase CstB | - |
| GDK20_RS00235 (SAKG22_00460) | - | 53239..54303 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| GDK20_RS00240 (SAKG22_00470) | cstR | 54439..54699 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| GDK20_RS00245 (SAKG22_00480) | - | 54699..55337 (+) | 639 | Protein_44 | sulfite exporter TauE/SafE family protein | - |
| GDK20_RS00255 (SAKG22_00490) | - | 55682..56344 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| GDK20_RS00270 (SAKG22_00500) | erm(A) | 56878..57609 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| GDK20_RS00275 (SAKG22_00510) | - | 57735..58517 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| GDK20_RS00280 (SAKG22_00520) | - | 58668..59045 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| GDK20_RS00285 (SAKG22_00530) | - | 59052..60944 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| GDK20_RS00290 (SAKG22_00540) | - | 60941..62026 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| GDK20_RS00295 (SAKG22_00550) | - | 62145..62462 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| GDK20_RS00300 (SAKG22_00560) | - | 62483..62989 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| GDK20_RS00305 (SAKG22_00570) | - | 63007..63318 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| GDK20_RS00310 (SAKG22_00580) | - | 63405..63755 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| GDK20_RS00315 (SAKG22_00590) | ccrB | 64273..65901 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| GDK20_RS00320 (SAKG22_00600) | ccrA | 65923..67272 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| GDK20_RS00325 (SAKG22_00610) | - | 67506..69299 (-) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| GDK20_RS00330 (SAKG22_00620) | - | 69299..69595 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| GDK20_RS00335 (SAKG22_00630) | - | 69788..70834 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| GDK20_RS00340 | - | 71085..72226 (-) | 1142 | Protein_60 | IS3-like element ISSau4 family transposase | - |
| GDK20_RS00345 (SAKG22_00670) | - | 72833..74005 (+) | 1173 | WP_000195429.1 | IS256-like element IS256 family transposase | - |
| GDK20_RS00350 (SAKG22_00680) | - | 74069..74995 (-) | 927 | Protein_62 | YfcC family protein | - |
| GDK20_RS00355 (SAKG22_00690) | - | 75717..76412 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| GDK20_RS00360 (SAKG22_00700) | - | 76387..79056 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| GDK20_RS00365 | kdpF | 79223..79303 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| GDK20_RS00370 (SAKG22_00720) | kdpA | 79324..81000 (+) | 1677 | WP_000029432.1 | potassium-transporting ATPase subunit KdpA | - |
| GDK20_RS00375 (SAKG22_00730) | - | 81019..83040 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| GDK20_RS00380 (SAKG22_00740) | - | 83056..83613 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| GDK20_RS00385 (SAKG22_00750) | - | 84158..85027 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| GDK20_RS00390 (SAKG22_00760) | - | 85037..85933 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| GDK20_RS00400 (SAKG22_00790) | - | 87052..87678 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| GDK20_RS00405 (SAKG22_00800) | - | 87793..89301 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| GDK20_RS00410 | - | 89551..89685 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| GDK20_RS00415 | - | 89649..89741 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| GDK20_RS00420 (SAKG22_00810) | - | 89888..91633 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| GDK20_RS00425 (SAKG22_00820) | - | 91731..92086 (-) | 356 | Protein_76 | tRNA-dihydrouridine synthase | - |
| GDK20_RS00430 | - | 92391..92479 (-) | 89 | Protein_77 | hypothetical protein | - |
| GDK20_RS00435 (SAKG22_00830) | - | 92577..93332 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| GDK20_RS00440 (SAKG22_00840) | cstR | 93332..93592 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| GDK20_RS00445 (SAKG22_00850) | cstA | 93729..94793 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| GDK20_RS00450 (SAKG22_00860) | cstB | 94824..96158 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| GDK20_RS00455 (SAKG22_00870) | sqr | 96177..97370 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| GDK20_RS15580 | - | 97637..97851 (-) | 215 | Protein_83 | universal stress protein | - |
| GDK20_RS00470 (SAKG22_00880) | - | 98037..99023 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| GDK20_RS00475 (SAKG22_00890) | - | 99332..99535 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| GDK20_RS00480 (SAKG22_00900) | - | 99584..99880 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| GDK20_RS00485 (SAKG22_00910) | - | 100088..100690 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| GDK20_RS00490 (SAKG22_00920) | - | 100957..104109 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=72797 GDK20_RS00315 WP_001186602.1 64273..65901(-) (ccrB) [Staphylococcus aureus strain KG-22]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=72797 GDK20_RS00315 WP_001186602.1 64273..65901(-) (ccrB) [Staphylococcus aureus strain KG-22]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |