Detailed information NTG0072750

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GDK21_RS14655
• Genome accession: NZ_AP019542
• Coordinates: 2843514..2844401 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain KG-03
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2838514..2849401

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GDK21_RS14620	-	2838533..2838625 (+)	93	WP_010956583.1	hypothetical protein	-
GDK21_RS14625 (SAKG03_26910)	-	2838733..2839230 (-)	498	WP_001065268.1	glutathione peroxidase	-
GDK21_RS14630 (SAKG03_26920)	-	2839240..2839500 (-)	261	WP_001791974.1	hypothetical protein	-
GDK21_RS14640	-	2839882..2839995 (-)	114	Protein_2792	hypothetical protein	-
GDK21_RS14645 (SAKG03_26930)	-	2840654..2842654 (-)	2001	WP_000776751.1	ABC transporter permease	-
GDK21_RS14650 (SAKG03_26940)	-	2842651..2843406 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
GDK21_RS14655 (SAKG03_26950)	braS	2843514..2844401 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GDK21_RS14660 (SAKG03_26960)	braR	2844412..2845077 (-)	666	WP_152064787.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GDK21_RS14665 (SAKG03_26970)	-	2845103..2845303 (-)	201	WP_000604730.1	hypothetical protein	-
GDK21_RS14670 (SAKG03_26980)	-	2845501..2846925 (+)	1425	WP_000953755.1	alkaline phosphatase	-
GDK21_RS15135	-	2846995..2847105 (+)	111	Protein_2799	hypothetical protein	-
GDK21_RS14680 (SAKG03_27000)	-	2847208..2847663 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GDK21_RS14685 (SAKG03_27010)	-	2847908..2848669 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=72750 GDK21_RS14655 WP_000143425.1 2843514..2844401(-) (braS) [Staphylococcus aureus strain KG-03]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=72750 GDK21_RS14655 WP_000143425.1 2843514..2844401(-) (braS) [Staphylococcus aureus strain KG-03]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1