Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   N2A94_RS05830 Genome accession   NZ_CP104048
Coordinates   1132726..1135014 (+) Length   762 a.a.
NCBI ID   WP_013794152.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP20     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127726..1140014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A94_RS05800 (N2A94_05800) - 1127794..1127928 (-) 135 WP_003107303.1 FeoB-associated Cys-rich membrane protein -
  N2A94_RS05805 (N2A94_05805) feoB 1127928..1130081 (-) 2154 WP_045407130.1 ferrous iron transport protein B -
  N2A94_RS05810 (N2A94_05810) - 1130099..1130557 (-) 459 WP_013794150.1 ferrous iron transport protein A -
  N2A94_RS05815 (N2A94_05815) - 1130669..1131403 (-) 735 WP_003102516.1 amino acid ABC transporter ATP-binding protein -
  N2A94_RS05820 (N2A94_05820) - 1131400..1132089 (-) 690 WP_013794151.1 amino acid ABC transporter permease -
  N2A94_RS05825 (N2A94_05825) - 1132216..1132446 (-) 231 WP_003105222.1 DUF1797 family protein -
  N2A94_RS05830 (N2A94_05830) clpE 1132726..1135014 (+) 2289 WP_013794152.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  N2A94_RS05835 (N2A94_05835) - 1135133..1135582 (+) 450 WP_013794153.1 NUDIX hydrolase -
  N2A94_RS05840 (N2A94_05840) - 1135631..1135939 (+) 309 WP_003108176.1 DUF1827 family protein -
  N2A94_RS05845 (N2A94_05845) ileS 1136005..1138800 (-) 2796 WP_013794154.1 isoleucine--tRNA ligase -
  N2A94_RS05850 (N2A94_05850) - 1139057..1139821 (-) 765 WP_003107309.1 DivIVA domain-containing protein -

Sequence

Protein


Download         Length: 762 a.a.        Molecular weight: 85070.22 Da        Isoelectric Point: 4.9026

>NTDB_id=727352 N2A94_RS05830 WP_013794152.1 1132726..1135014(+) (clpE) [Streptococcus parauberis strain KSP20]
MLCQNCQLNEASIHLYTNVNGKQKQIDLCQNCYQIMKTDANNSILGGIGSRSEKKQDPMNPFFDDFFGDLNNFRSFGNLP
NTPPTQAGGNNGGNNGKIPNQQGSRNQNAQATQQPKGLLEEFGINVTEIARKGGIDPVIGRDEEITRVIEILNRRTKNNP
VLIGEPGVGKTAVVEGLAQKIVDSDVPYKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEI
VGAGNAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQTKYEDYHHV
KYTDDAIIAAATLSNRYIQDRFLPDKAIDLLDEAGSKLNLTLTFVDPKEIDQRLVEAENLKAQATRDEDYERAAYFRDQI
IKYKELQKQKVDEEDTPIITEKTIEDILEDKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLG
TPNRPIGSFLFVGPTGVGKTELSKQLAIELFGTADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYS
LILLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTSTNEASVGFGAAREGRTSSVLGQLTNFFNP
EFMNRFDGIIEFQTLSKDNLLHIVDLMLEDVNNRLSQNGLHLDVTNKVKEKLVDLGYNPKMGARPLRRTIQDYIEDAITD
FYLENPSEKELKAMMTSNGNIIIKSAKKSNSPVEDQTKSYEN

Nucleotide


Download         Length: 2289 bp        

>NTDB_id=727352 N2A94_RS05830 WP_013794152.1 1132726..1135014(+) (clpE) [Streptococcus parauberis strain KSP20]
ATGCTCTGTCAGAATTGTCAATTAAATGAAGCTTCAATCCATTTATATACCAATGTTAATGGGAAACAAAAGCAAATTGA
TTTATGTCAAAATTGCTATCAAATAATGAAAACGGATGCGAATAATTCAATATTAGGGGGAATTGGTTCGCGTTCAGAAA
AAAAACAAGACCCAATGAATCCATTCTTTGATGACTTTTTCGGTGATTTGAATAACTTTCGATCTTTCGGAAATCTACCT
AATACACCTCCAACTCAGGCAGGTGGAAACAACGGTGGAAATAATGGGAAAATTCCTAACCAACAGGGCTCTCGTAATCA
AAATGCACAAGCTACTCAACAGCCTAAAGGCTTACTAGAAGAGTTTGGTATCAATGTTACGGAAATTGCCCGTAAAGGAG
GTATTGACCCTGTTATAGGTCGTGACGAAGAGATTACACGTGTCATTGAAATTCTCAATCGTCGTACAAAGAATAATCCA
GTTCTAATTGGCGAACCCGGTGTTGGTAAAACTGCTGTCGTTGAAGGTTTAGCTCAAAAAATTGTGGACAGTGATGTCCC
ATATAAACTTCAAGGTAAACAAGTGATTCGTTTAGATGTTGTTAGTTTAGTCCAAGGAACTGGAATCCGTGGTCAATTTG
AAGAACGAATGCAAAAACTGATGGAAGAAATAAGAAACCGTCAAGATGTTATCTTATTCATTGATGAAATTCACGAAATT
GTTGGAGCCGGTAATGCAGGTGATGGCAACATGGACGCTGGAAATATCTTAAAACCTGCACTTGCTCGTGGTGAATTACA
GTTAGTTGGTGCTACTACACTTAATGAGTATCGAATTATTGAGAAAGATGCCGCCTTAGAACGACGTATGCAACCTGTTA
AGGTTGATGAGCCTTCTGTTGAAGAAACAATTACCATCTTAAAAGGGATCCAGACTAAGTACGAAGATTATCATCATGTT
AAGTATACAGATGATGCTATCATTGCTGCTGCGACACTTTCTAATCGATATATTCAAGATCGCTTCCTTCCAGACAAAGC
AATTGACTTACTCGATGAAGCCGGCTCAAAATTGAACTTGACGTTAACTTTTGTTGATCCAAAAGAAATAGATCAACGTC
TTGTCGAAGCCGAAAACTTAAAAGCGCAGGCTACACGAGATGAAGACTATGAGCGCGCAGCTTATTTCCGCGACCAAATT
ATCAAATATAAAGAGTTACAAAAGCAAAAAGTTGATGAAGAAGATACCCCAATCATTACTGAGAAAACAATTGAAGATAT
CTTAGAGGACAAAACCAATATCCCTGTGGGTGATTTGAAAGAAAAAGAACAATCACAATTGATTCACCTGGCTGAAGATT
TGAAGAGTCATGTCATTGGTCAAGACGATGCTGTTGATAAAATTGCTAAAGCTATTCGTCGTAACCGGGTCGGTCTAGGT
ACGCCAAATCGACCAATCGGTTCATTCTTATTCGTGGGTCCTACAGGTGTAGGGAAAACTGAGTTATCTAAGCAATTAGC
AATTGAACTTTTTGGTACAGCCGATAATATGATTCGTTTTGATATGTCAGAGTACATGGAGAAACATGCCGTTGCTAAGT
TGGTTGGTGCCCCTCCTGGCTATGTCGGATATGAGGAAGCCGGTCAATTAACGGAAAAAGTCCGTCGCAATCCTTATTCA
CTCATTTTGCTAGATGAAATTGAAAAAGCTCACCCTGATGTTATGCACATGTTCCTTCAAGTTTTAGACGATGGTCGTTT
GACTGATGGGCAAGGCCGGACAGTTAGCTTTAAAGATACCATCATCATTATGACTTCTAATGCCGGGACAAGTACTAATG
AAGCCTCTGTCGGATTTGGGGCAGCCCGCGAAGGACGAACAAGTTCAGTTCTGGGACAATTAACAAATTTCTTTAATCCA
GAATTTATGAACCGTTTTGATGGTATTATTGAATTCCAAACATTAAGCAAAGATAATCTATTACATATTGTTGATTTGAT
GTTAGAAGATGTCAACAATCGCCTCTCTCAAAATGGTCTTCACCTTGATGTGACCAATAAAGTTAAAGAGAAATTAGTCG
ATCTTGGTTATAATCCAAAAATGGGTGCTCGTCCATTAAGAAGAACTATTCAAGATTACATTGAAGATGCTATTACTGAT
TTCTACTTGGAAAATCCAAGTGAAAAAGAGCTTAAAGCAATGATGACTAGTAATGGAAATATCATTATTAAATCAGCAAA
AAAATCTAATTCACCTGTGGAAGATCAAACCAAGTCTTACGAAAATTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(655-729)

ATPase family associated with various cellular activities (AAA) (AAA)

(161-281)

AAA lid domain (AAA_lid_9)

(299-396)

AAA domain (Cdc48 subfamily) (AAA_2)

(484-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

83.837

99.869

0.837
  clpE Streptococcus pneumoniae Rx1

83.712

98.294

0.823
  clpE Streptococcus pneumoniae D39

83.712

98.294

0.823
  clpE Streptococcus pneumoniae R6

83.712

98.294

0.823
  clpE Streptococcus pneumoniae TIGR4

83.578

98.294

0.822
  clpC Lactococcus lactis subsp. cremoris KW2

74.373

99.344

0.739
  clpC Bacillus subtilis subsp. subtilis str. 168

51.529

85.827

0.442
  clpC Streptococcus pneumoniae Rx1

46.635

83.858

0.391
  clpC Streptococcus pneumoniae TIGR4

46.635

83.858

0.391
  clpC Streptococcus pneumoniae D39

46.635

83.858

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.72

82.021

0.383
  clpC Streptococcus mutans UA159

47.317

80.709

0.382
  clpC Streptococcus thermophilus LMD-9

46.24

82.021

0.379
  clpC Streptococcus thermophilus LMG 18311

45.92

82.021

0.377