Detailed information NTG0727134

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: P1Y72_RS00365
• Genome accession: NZ_CP119599
• Coordinates: 79927..83556 (+)
• Length: 1209 a.a.
• NCBI ID: WP_278248277.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1133
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 74927..88556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1Y72_RS00355 (P1Y72_00355)	-	75644..76561 (-)	918	WP_012560586.1	neutral zinc metallopeptidase	-
P1Y72_RS00360 (P1Y72_00360)	rexB	76712..79927 (+)	3216	WP_159330881.1	ATP-dependent nuclease subunit B	Machinery gene
P1Y72_RS00365 (P1Y72_00365)	rexA	79927..83556 (+)	3630	WP_278248277.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
P1Y72_RS00370 (P1Y72_00370)	-	83696..84508 (+)	813	WP_023078819.1	transporter substrate-binding domain-containing protein	-
P1Y72_RS00375 (P1Y72_00375)	rpsU	84649..84825 (+)	177	WP_000048058.1	30S ribosomal protein S21	-
P1Y72_RS00380 (P1Y72_00380)	mscL	84953..85315 (-)	363	WP_002990299.1	large conductance mechanosensitive channel protein MscL	-
P1Y72_RS00385 (P1Y72_00385)	dnaG	85445..87259 (+)	1815	WP_159330880.1	DNA primase	-
P1Y72_RS00390 (P1Y72_00390)	rpoD	87268..88377 (+)	1110	WP_002985187.1	RNA polymerase sigma factor RpoD	-

Sequence

Protein

• Length: 1209 a.a.
• Molecular weight: 138923.05 Da
• Isoelectric Point: 6.5804

>NTDB_id=727134 P1Y72_RS00365 WP_278248277.1 79927..83556(+) (rexA) [Streptococcus pyogenes strain 1133]
MSFAPFLSPEAIKHLQENERYSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFT
VKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLK
QEVFSKLFNEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDI
ELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVT
VSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIR
QSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFR
SQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKE
IIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRIINNPRNDYALVALLRSP
MFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFND
RFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQF
PYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVA
MTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQ
TPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEKSSRSLSDFTLP
HFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYRE
APFAILKLDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMG
GGKPEIVEV

Nucleotide

• Length: 3630 bp

>NTDB_id=727134 P1Y72_RS00365 WP_278248277.1 79927..83556(+) (rexA) [Streptococcus pyogenes strain 1133]
ATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTACAGTGATCAGTCTCAAAA
ACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAA
CCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACT
GTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCAAAT
GAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAG
TAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAG
CAAGAGGTGTTTAGCAAACTCTTTAATGAGTTTATGAATCAAAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAATTT
TTCTGGTAATTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATC
CAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGATATT
GAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGAC
TAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTA
AATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGACCTTATACCATCTGGGAATGATGTTACA
GTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTTAAT
GTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTGTCA
AAATACAAGAAAGCGCTTTTGAATTTTCAGATATTGCACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGC
CAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCTGAC
CTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTC
AGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGT
AGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATACGA
TGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATA
ATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGCGAGGTTACAATTGTTGCCAAAGAA
ATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATAT
CATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAG
TGATGGTTATGTTAGATACATTACGCATCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCG
ATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGA
CAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATGTTT
TTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTCAATGAT
CGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGC
TAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATG
ACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAATTT
CCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCAGCA
CGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGG
AAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTACTGTATGTTGCT
ATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAAAAA
GTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATATAT
TTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAA
ACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGA
AGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGGCAA
CTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCA
CATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTC
AAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATC
TCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAA
GCACCATTTGCTATTTTAAAACTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTTTTT
GTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAAC
AACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGA
GGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C) (473-891)

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1045-1196)

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-463)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	48.371	100	0.491