Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   P1K34_RS00665 Genome accession   NZ_CP119598
Coordinates   104530..104814 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain 1042     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99530..109814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1K34_RS00640 (P1K34_00640) - 101476..101841 (+) 366 WP_002986560.1 DUF1033 family protein -
  P1K34_RS00645 (P1K34_00645) comGA 101934..102872 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  P1K34_RS00650 (P1K34_00650) comGB 102808..103842 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  P1K34_RS00655 (P1K34_00655) comGC 103844..104170 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  P1K34_RS00660 (P1K34_00660) comGD 104145..104573 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  P1K34_RS00665 (P1K34_00665) comGE 104530..104814 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  P1K34_RS00670 (P1K34_00670) comGF 104807..105241 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  P1K34_RS00675 (P1K34_00675) comGG 105225..105551 (+) 327 WP_136274078.1 competence type IV pilus minor pilin ComGG -
  P1K34_RS00680 (P1K34_00680) comGH 105649..106602 (+) 954 WP_136274080.1 class I SAM-dependent methyltransferase Machinery gene
  P1K34_RS00685 (P1K34_00685) - 106661..107857 (+) 1197 WP_023612537.1 acetate kinase -
  P1K34_RS00690 (P1K34_00690) - 108044..108352 (+) 309 WP_010921804.1 hypothetical protein -
  P1K34_RS00695 (P1K34_00695) proC 108435..109205 (-) 771 WP_136274084.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=727045 P1K34_RS00665 WP_002987779.1 104530..104814(+) (comGE) [Streptococcus pyogenes strain 1042]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=727045 P1K34_RS00665 WP_002987779.1 104530..104814(+) (comGE) [Streptococcus pyogenes strain 1042]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383