Detailed information NTG0727031

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: P1J77_RS08710
• Genome accession: NZ_CP119597
• Coordinates: 1781296..1782063 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1039
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1776296..1787063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1J77_RS08695 (P1J77_08695)	hexB	1776754..1778736 (-)	1983	WP_159330786.1	DNA mismatch repair endonuclease MutL	Machinery gene
P1J77_RS08700 (P1J77_08700)	-	1778831..1779976 (-)	1146	WP_002992191.1	site-specific integrase	-
P1J77_RS08705 (P1J77_08705)	-	1780304..1780447 (+)	144	WP_002992192.1	putative holin-like toxin	-
P1J77_RS08710 (P1J77_08710)	irvR	1781296..1782063 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
P1J77_RS08715 (P1J77_08715)	-	1782217..1782423 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
P1J77_RS08720 (P1J77_08720)	-	1782457..1782630 (+)	174	Protein_1662	helix-turn-helix transcriptional regulator	-
P1J77_RS08725 (P1J77_08725)	-	1782678..1783085 (+)	408	WP_002992501.1	hypothetical protein	-
P1J77_RS08730 (P1J77_08730)	-	1783098..1783220 (+)	123	WP_002992500.1	hypothetical protein	-
P1J77_RS08735 (P1J77_08735)	-	1783503..1784024 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
P1J77_RS08740 (P1J77_08740)	-	1784269..1784601 (+)	333	WP_002992497.1	hypothetical protein	-
P1J77_RS08745 (P1J77_08745)	-	1784598..1784819 (+)	222	WP_010922763.1	hypothetical protein	-
P1J77_RS08750 (P1J77_08750)	-	1784822..1785013 (+)	192	WP_010922764.1	hypothetical protein	-
P1J77_RS08755 (P1J77_08755)	-	1785025..1785354 (+)	330	WP_003058810.1	hypothetical protein	-
P1J77_RS08760 (P1J77_08760)	-	1785357..1785629 (+)	273	WP_001100459.1	hypothetical protein	-
P1J77_RS08765 (P1J77_08765)	-	1785630..1786487 (+)	858	WP_136098354.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=727031 P1J77_RS08710 WP_003058809.1 1781296..1782063(-) (irvR) [Streptococcus pyogenes strain 1039]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=727031 P1J77_RS08710 WP_003058809.1 1781296..1782063(-) (irvR) [Streptococcus pyogenes strain 1039]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4