Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   P1J77_RS01915 Genome accession   NZ_CP119597
Coordinates   398903..399565 (+) Length   220 a.a.
NCBI ID   WP_136110879.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1039     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 393903..404565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1J77_RS01895 (P1J77_01895) - 394777..396777 (+) 2001 WP_010922439.1 potassium transporter Kup -
  P1J77_RS01900 (P1J77_01900) - 396801..397079 (-) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  P1J77_RS01905 (P1J77_01905) - 397069..397845 (-) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  P1J77_RS01910 (P1J77_01910) - 397963..398703 (+) 741 WP_011054661.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  P1J77_RS01915 (P1J77_01915) comEA/celA/cilE 398903..399565 (+) 663 WP_136110879.1 ComEA family DNA-binding protein Machinery gene
  P1J77_RS01920 (P1J77_01920) comEC/celB 399546..401789 (+) 2244 WP_136274012.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  P1J77_RS01925 (P1J77_01925) holA 401860..402900 (+) 1041 WP_111689533.1 DNA polymerase III subunit delta -
  P1J77_RS01930 (P1J77_01930) sodA 402997..403602 (+) 606 WP_002983977.1 superoxide dismutase SodA -
  P1J77_RS01935 (P1J77_01935) - 403769..403996 (+) 228 WP_030126413.1 hypothetical protein -
  P1J77_RS01940 (P1J77_01940) - 403981..404229 (+) 249 WP_010922432.1 serine hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24634.43 Da        Isoelectric Point: 6.7451

>NTDB_id=726966 P1J77_RS01915 WP_136110879.1 398903..399565(+) (comEA/celA/cilE) [Streptococcus pyogenes strain 1039]
MLDELLIKGKSFLRERYFPPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETANKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=726966 P1J77_RS01915 WP_136110879.1 398903..399565(+) (comEA/celA/cilE) [Streptococcus pyogenes strain 1039]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCCGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAACAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4