Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PZ486_RS01245 Genome accession   NZ_CP119571
Coordinates   225133..225852 (+) Length   239 a.a.
NCBI ID   WP_001217723.1    Uniprot ID   -
Organism   Staphylococcus aureus strain N08CSA36     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 220133..230852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PZ486_RS01220 (PZ486_01220) - 220213..221193 (+) 981 WP_000427769.1 dipeptide ABC transporter ATP-binding protein -
  PZ486_RS01225 (PZ486_01225) opp4B 221186..222148 (+) 963 WP_000239820.1 oligopeptide ABC transporter permease -
  PZ486_RS01230 (PZ486_01230) opp4C 222160..223041 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  PZ486_RS01235 (PZ486_01235) trpS 223083..224072 (-) 990 WP_031589556.1 tryptophan--tRNA ligase -
  PZ486_RS01240 (PZ486_01240) spxA 224367..224762 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  PZ486_RS01245 (PZ486_01245) mecA 225133..225852 (+) 720 WP_001217723.1 adaptor protein MecA Regulator
  PZ486_RS01250 (PZ486_01250) coiA 225973..226959 (+) 987 WP_000959292.1 competence protein CoiA family protein Machinery gene
  PZ486_RS01255 (PZ486_01255) pepF 227007..228815 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  PZ486_RS01260 (PZ486_01260) yjbH 229275..230081 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  PZ486_RS01265 (PZ486_01265) - 230104..230469 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28285.17 Da        Isoelectric Point: 4.1548

>NTDB_id=726525 PZ486_RS01245 WP_001217723.1 225133..225852(+) (mecA) [Staphylococcus aureus strain N08CSA36]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFDQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 720 bp        

>NTDB_id=726525 PZ486_RS01245 WP_001217723.1 225133..225852(+) (mecA) [Staphylococcus aureus strain N08CSA36]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATT
AGAAGGTGAAGATCAATTAGAAGAATTATTCGATCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGT
CTTCAGCACGTAAAAATACAAGAACAATTATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGC
AATCCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCA
TGTTGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATT
TAAATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.975

99.163

0.377