Detailed information NTG0726428

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: P1T45_RS11025
• Genome accession: NZ_CP119427
• Coordinates: 2085374..2087929 (-)
• Length: 851 a.a.
• NCBI ID: WP_003108889.1
• Uniprot ID: A0ABN0IP02
• Organism: Streptococcus parauberis strain KSP45
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2080374..2092929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1T45_RS10990 (P1T45_10995)	-	2080674..2081093 (+)	420	WP_003108900.1	DUF1492 domain-containing protein	-
P1T45_RS10995 (P1T45_11000)	-	2081099..2081533 (+)	435	WP_003108899.1	DUF1492 domain-containing protein	-
P1T45_RS11000 (P1T45_11005)	-	2081694..2082356 (-)	663	WP_003108897.1	hypothetical protein	-
P1T45_RS11005 (P1T45_11010)	-	2082552..2083052 (-)	501	WP_308695475.1	hypothetical protein	-
P1T45_RS11010 (P1T45_11015)	-	2083046..2083462 (-)	417	WP_308695478.1	hypothetical protein	-
P1T45_RS11015 (P1T45_11020)	-	2084122..2084736 (+)	615	WP_003107889.1	CadD family cadmium resistance transporter	-
P1T45_RS11020 (P1T45_11025)	-	2084752..2085081 (+)	330	WP_003108890.1	metalloregulator ArsR/SmtB family transcription factor	-
P1T45_RS11025 (P1T45_11030)	hexA	2085374..2087929 (-)	2556	WP_003108889.1	DNA mismatch repair protein MutS	Machinery gene
P1T45_RS11030 (P1T45_11035)	-	2087916..2088269 (-)	354	WP_003104802.1	YlbF family regulator	-
P1T45_RS11035 (P1T45_11040)	argR	2088266..2088703 (-)	438	WP_003105697.1	arginine repressor	-
P1T45_RS11040 (P1T45_11045)	argS	2088990..2090678 (+)	1689	WP_003107896.1	arginine--tRNA ligase	-
P1T45_RS11045 (P1T45_11050)	-	2090714..2091592 (-)	879	WP_003102528.1	YitT family protein	-
P1T45_RS11050 (P1T45_11055)	-	2091648..2092526 (-)	879	WP_003108886.1	YitT family protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95498.18 Da
• Isoelectric Point: 4.9392

>NTDB_id=726428 P1T45_RS11025 WP_003108889.1 2085374..2087929(-) (hexA) [Streptococcus parauberis strain KSP45]
MTEPKVSPGMQQYLDIKVNYPDAFLLFRMGDFYELFYDDAVKAAQILEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
EQGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPTSSNNFLVAIDYNGSNYGLAYMDLATGEFFVTALEDFAS
ICSEILNLKAKEVLVGYDLSGQEEEILVKQYNLLLSYEKEEIDDSKLLDNNLSIIEKMVASKLLAYVHHTQMRDLIHLQK
VVHYEINDYLQMSYATKSSLDLLENARTGKKHGSLYWLLDQTKTAMGMRLLRAWIDRPLISKEAVIQRQEIIQVLLDNFI
ERSDLSDSLKGVYDIERLSSRVSFGKVNPKDLLQLGHTLAQVPTIKAILESMDSPHLEGLIAGIDPILELEHLIQSAIDP
DAPATISEGNIIKTGFDKQLDHYRKVMKEGTGWIADIEMKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTMELAKIEGQMLEAREESSTLEYDIFMQLRSRVENYIDRLQQLAKSIAAVDVLQSLAVVAEKNHYIRPSFT
DHQEINIINGRHAVVEKVMSVKEYIPNTIQFSQETNIQLITGPNMSGKSTYMRQLALTSIMAQLGSYVAADLAEIPIFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKGASPRSLILFDELGRGTATYDGMALAQSIIEFIHDHVGAKTMFATHYHEL
TDLSSRLKSLINVHVATLEENGEVTFLHKIAQGPADKSYGIHVAKIAGLPKELLQRADAILQKLENQSTQLTLVANAEES
QQAQTDKNQQLELFAPDAEENQVIEQLKAMDVINMTPMEAMTALYELKKNL

Nucleotide

• Length: 2556 bp

>NTDB_id=726428 P1T45_RS11025 WP_003108889.1 2085374..2087929(-) (hexA) [Streptococcus parauberis strain KSP45]
ATGACAGAGCCTAAAGTTTCTCCTGGAATGCAACAGTATCTGGACATAAAAGTAAATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTACGAATTATTTTATGACGATGCTGTTAAAGCAGCTCAAATATTAGAAATTGGTTTAACCAGTC
GCAACAAGAATGCTGAAAACCCAATACCCATGGCGGGAGTGCCCCACCATTCAGCACAACAATATATTGATGTTTTAATT
GAGCAAGGTTATAAAGTAGCCATTGCTGAACAAATGGAAGATCCTAAAAAAGCTGTCGGCGTTGTTAAACGTGAAGTGGT
TCAAGTGATTACTCCCGGAACTGTTGTCGATTCAGCTAAACCAACCAGTTCAAATAATTTCTTAGTTGCGATTGATTATA
ATGGTAGCAATTATGGTTTGGCTTATATGGACCTAGCTACTGGTGAATTCTTTGTGACAGCTCTGGAGGATTTCGCAAGT
ATTTGCAGTGAAATCTTAAATTTGAAAGCTAAAGAAGTTCTTGTTGGATATGACTTAAGTGGCCAAGAAGAAGAAATTTT
AGTAAAACAATATAATCTATTACTATCTTATGAAAAGGAAGAAATTGATGACAGTAAACTTTTAGATAATAATTTGTCAA
TCATTGAAAAAATGGTCGCAAGTAAGTTATTAGCTTATGTGCACCATACGCAAATGCGCGACCTAATTCACCTTCAAAAA
GTCGTTCACTATGAGATAAACGATTACTTACAAATGTCTTATGCTACTAAATCAAGCTTAGATCTACTAGAAAATGCTCG
AACCGGGAAAAAACATGGCAGTCTATACTGGTTATTAGATCAAACCAAGACAGCAATGGGGATGCGACTACTGCGTGCTT
GGATTGACCGTCCTCTAATTAGTAAAGAAGCTGTAATCCAGCGCCAAGAAATTATTCAAGTCTTACTTGATAATTTCATT
GAGCGTTCTGATTTAAGTGATAGCTTAAAAGGTGTCTATGACATTGAAAGACTATCAAGTCGTGTATCTTTCGGTAAGGT
TAATCCCAAAGACTTATTGCAACTAGGACATACCTTAGCTCAAGTGCCAACAATTAAAGCCATTTTGGAAAGTATGGATA
GTCCTCACTTAGAGGGACTCATTGCTGGTATCGACCCAATCCTTGAGTTAGAACACCTAATTCAATCAGCTATTGATCCA
GATGCGCCTGCAACAATTAGTGAAGGTAATATCATCAAAACTGGTTTTGACAAACAATTGGATCATTATCGGAAGGTCAT
GAAAGAAGGCACGGGCTGGATAGCAGATATTGAAATGAAAGAGCGCCAAGCAAGTGGTATTAACAATCTTAAAATTGATT
ACAATAAAAAAGATGGTTACTATTTCCATGTCACAAACTCTAATTTATCCCTTGTTCCGGACCATTTCTTTAGGAAAGCA
ACCTTAAAAAATTCTGAGCGTTATGGAACCATGGAATTAGCTAAAATTGAAGGACAAATGTTGGAAGCTAGAGAAGAATC
CTCAACTCTTGAGTATGATATCTTTATGCAATTGCGCTCACGAGTGGAAAATTATATTGATCGCCTTCAACAACTTGCCA
AATCAATTGCTGCCGTCGATGTCCTCCAAAGTTTAGCAGTTGTGGCTGAGAAAAACCATTACATCAGACCAAGTTTCACC
GACCATCAAGAAATTAATATCATTAATGGTCGCCATGCAGTGGTTGAAAAAGTGATGAGCGTCAAAGAATATATTCCCAA
CACCATTCAATTTAGTCAAGAAACGAATATCCAGCTCATTACAGGACCTAATATGAGTGGTAAATCAACTTATATGAGGC
AGTTAGCTTTAACCAGTATTATGGCCCAACTTGGTTCTTATGTGGCAGCAGACCTTGCAGAAATTCCCATTTTTGATGCT
ATCTTTACAAGAATTGGCGCAGCAGATGACCTGATTTCTGGACAATCGACATTCATGGTCGAAATGATGGAGGCCAACCA
AGCAATCAAAGGCGCAAGCCCACGGTCTTTAATTCTATTTGACGAATTAGGAAGAGGAACAGCTACTTATGATGGCATGG
CGCTAGCTCAATCAATTATTGAGTTTATCCATGACCACGTGGGAGCAAAAACAATGTTTGCCACCCATTATCATGAGTTG
ACAGACCTGTCAAGCCGCCTAAAAAGCCTGATAAATGTCCATGTCGCAACCTTGGAAGAAAATGGCGAAGTGACTTTCCT
TCATAAGATTGCCCAAGGACCGGCGGATAAATCCTACGGCATCCACGTGGCCAAAATTGCTGGGCTGCCAAAAGAACTCT
TACAACGTGCGGATGCCATTCTCCAAAAATTAGAGAACCAATCGACTCAGTTGACACTAGTTGCCAATGCAGAGGAATCC
CAACAAGCACAGACCGACAAGAATCAACAATTGGAACTCTTTGCCCCAGATGCTGAGGAGAACCAAGTCATTGAGCAATT
GAAAGCCATGGATGTTATCAATATGACCCCAATGGAGGCTATGACTGCCCTCTATGAACTGAAAAAGAACTTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-238)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	70.838	99.53	0.705
mutS	Pseudomonas stutzeri strain ATCC 17587	36.468	100	0.374