Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NX081_RS05930 Genome accession   NZ_CP103856
Coordinates   1150337..1150993 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM116265     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1145337..1155993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX081_RS05900 (NX081_05900) oppF 1145867..1146784 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NX081_RS05905 (NX081_05905) - 1146891..1148078 (+) 1188 WP_079891086.1 putative glycoside hydrolase -
  NX081_RS05910 (NX081_05910) - 1148196..1148774 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NX081_RS05915 (NX081_05915) spx 1148953..1149348 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NX081_RS05920 (NX081_05920) - 1149405..1150061 (-) 657 WP_060562158.1 TerC family protein -
  NX081_RS05925 (NX081_05925) - 1150244..1150354 (+) 111 Protein_1104 adaptor protein MecA -
  NX081_RS05930 (NX081_05930) mecA 1150337..1150993 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NX081_RS05935 (NX081_05935) - 1151144..1152304 (+) 1161 WP_060562159.1 competence protein CoiA family protein -
  NX081_RS05940 (NX081_05940) pepF 1152532..1154361 (+) 1830 WP_101536289.1 oligoendopeptidase F Regulator
  NX081_RS05945 (NX081_05945) - 1154399..1154566 (-) 168 WP_003155026.1 hypothetical protein -
  NX081_RS05950 (NX081_05950) spxH 1154852..1155754 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=726074 NX081_RS05930 WP_003155032.1 1150337..1150993(+) (mecA) [Bacillus velezensis strain SRCM116265]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=726074 NX081_RS05930 WP_003155032.1 1150337..1150993(+) (mecA) [Bacillus velezensis strain SRCM116265]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895