Detailed information NTG0726005

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NYF25_RS13750
• Genome accession: NZ_CP103850
• Coordinates: 2738758..2739645 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NRL 02/947
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2733758..2744645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NYF25_RS13720 (NYF25_13720)	-	2733777..2733869 (+)	93	WP_010956583.1	hypothetical protein	-
NYF25_RS13725 (NYF25_13725)	-	2733977..2734474 (-)	498	WP_001065268.1	glutathione peroxidase	-
NYF25_RS13730 (NYF25_13730)	-	2734484..2734744 (-)	261	WP_001789910.1	hypothetical protein	-
NYF25_RS13735 (NYF25_13735)	-	2735126..2735239 (-)	114	WP_011447078.1	hypothetical protein	-
NYF25_RS13740 (NYF25_13740)	-	2735898..2737898 (-)	2001	WP_000776751.1	ABC transporter permease	-
NYF25_RS13745 (NYF25_13745)	-	2737895..2738650 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NYF25_RS13750 (NYF25_13750)	braS	2738758..2739645 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NYF25_RS13755 (NYF25_13755)	braR	2739656..2740321 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NYF25_RS13760 (NYF25_13760)	-	2740347..2740547 (-)	201	WP_000604728.1	hypothetical protein	-
NYF25_RS13765 (NYF25_13765)	-	2740745..2742169 (+)	1425	WP_000953744.1	alkaline phosphatase	-
NYF25_RS14245	-	2742229..2742330 (-)	102	WP_000731972.1	SE2200 family small protein	-
NYF25_RS13775 (NYF25_13775)	-	2742452..2742907 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NYF25_RS13780 (NYF25_13780)	-	2743152..2743913 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=726005 NYF25_RS13750 WP_000143419.1 2738758..2739645(-) (braS) [Staphylococcus aureus strain NRL 02/947]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=726005 NYF25_RS13750 WP_000143419.1 2738758..2739645(-) (braS) [Staphylococcus aureus strain NRL 02/947]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997