Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   NYF25_RS10600 Genome accession   NZ_CP103850
Coordinates   2125272..2125946 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NRL 02/947     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2116316..2141893 2125272..2125946 within 0


Gene organization within MGE regions


Location: 2116316..2141893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYF25_RS10540 (NYF25_10540) - 2116316..2116990 (+) 675 WP_001105960.1 IS6 family transposase -
  NYF25_RS10545 (NYF25_10545) - 2117498..2118157 (-) 660 WP_259425912.1 RibD family protein -
  NYF25_RS10550 (NYF25_10550) - 2118268..2118624 (-) 357 WP_000374054.1 WYL domain-containing protein -
  NYF25_RS10555 (NYF25_10555) - 2118648..2119220 (-) 573 WP_001079938.1 HTH domain-containing protein -
  NYF25_RS10560 (NYF25_10560) aph(3')-IIIa 2119496..2120290 (-) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  NYF25_RS10565 (NYF25_10565) sat4 2120383..2120925 (-) 543 WP_188348980.1 streptothricin N-acetyltransferase Sat4 -
  NYF25_RS10570 (NYF25_10570) - 2120922..2121557 (-) 636 Protein_2044 aminoglycoside 6-adenylyltransferase -
  NYF25_RS10575 (NYF25_10575) - 2121698..2122372 (-) 675 WP_001105960.1 IS6 family transposase -
  NYF25_RS10580 (NYF25_10580) - 2122429..2122605 (-) 177 Protein_2046 undecaprenyl-diphosphate phosphatase -
  NYF25_RS10585 (NYF25_10585) - 2122619..2123356 (-) 738 WP_000369394.1 ABC transporter permease -
  NYF25_RS10590 (NYF25_10590) - 2123349..2124278 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  NYF25_RS10595 (NYF25_10595) - 2124394..2125275 (-) 882 Protein_2049 sensor histidine kinase -
  NYF25_RS10600 (NYF25_10600) braR 2125272..2125946 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  NYF25_RS10605 (NYF25_10605) - 2126086..2126760 (-) 675 WP_001105960.1 IS6 family transposase -
  NYF25_RS10610 (NYF25_10610) - 2126952..2128364 (-) 1413 WP_000526300.1 PLP-dependent aminotransferase family protein -
  NYF25_RS10615 (NYF25_10615) - 2128463..2129434 (+) 972 WP_000053810.1 fatty acid desaturase family protein -
  NYF25_RS10620 (NYF25_10620) - 2129439..2130059 (+) 621 WP_000941203.1 LysE family transporter -
  NYF25_RS10625 (NYF25_10625) - 2130103..2130276 (+) 174 WP_000044738.1 hypothetical protein -
  NYF25_RS10630 (NYF25_10630) - 2130570..2131244 (-) 675 WP_001105960.1 IS6 family transposase -
  NYF25_RS10635 (NYF25_10635) msr(A) 2131718..2133184 (+) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  NYF25_RS10640 (NYF25_10640) - 2133283..2133852 (+) 570 Protein_2058 macrolide 2'-phosphotransferase -
  NYF25_RS10645 (NYF25_10645) - 2133846..2134553 (+) 708 Protein_2059 SulP family inorganic anion transporter -
  NYF25_RS10650 (NYF25_10650) - 2134567..2134980 (+) 414 WP_000278297.1 universal stress protein -
  NYF25_RS10655 (NYF25_10655) - 2135036..2135479 (+) 444 WP_012817960.1 hypothetical protein -
  NYF25_RS10660 (NYF25_10660) - 2136276..2136938 (-) 663 WP_259426033.1 RepB family plasmid replication initiator protein -
  NYF25_RS10665 (NYF25_10665) - 2136972..2137646 (-) 675 WP_001105960.1 IS6 family transposase -
  NYF25_RS10670 (NYF25_10670) - 2137703..2138260 (+) 558 Protein_2064 replication initiation factor domain-containing protein -
  NYF25_RS10675 (NYF25_10675) tet(K) 2138422..2139801 (+) 1380 WP_000492283.1 tetracycline efflux MFS transporter Tet(K) -
  NYF25_RS10680 (NYF25_10680) mobV 2139990..2141189 (+) 1200 WP_001829561.1 MobV family relaxase -
  NYF25_RS10685 (NYF25_10685) - 2141219..2141893 (+) 675 WP_001105960.1 IS6 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=726001 NYF25_RS10600 WP_000866106.1 2125272..2125946(-) (braR) [Staphylococcus aureus strain NRL 02/947]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=726001 NYF25_RS10600 WP_000866106.1 2125272..2125946(-) (braR) [Staphylococcus aureus strain NRL 02/947]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656