Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   NYF25_RS00220 Genome accession   NZ_CP103850
Coordinates   47617..48966 (-) Length   449 a.a.
NCBI ID   WP_000815648.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NRL 02/947     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 39202..52537 47617..48966 within 0


Gene organization within MGE regions


Location: 39202..52537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYF25_RS00180 (NYF25_00180) mecA 39202..41211 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  NYF25_RS00185 (NYF25_00185) - 41308..42294 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  NYF25_RS00190 (NYF25_00190) - 42266..42526 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  NYF25_RS00195 (NYF25_00195) - 42517..44124 (-) 1608 Protein_33 IS1182 family transposase -
  NYF25_RS00200 (NYF25_00200) - 44176..44682 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  NYF25_RS00205 (NYF25_00205) - 44697..45008 (-) 312 WP_000700851.1 DUF960 family protein -
  NYF25_RS00210 (NYF25_00210) - 45095..45445 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  NYF25_RS00215 (NYF25_00215) ccrB 45967..47595 (-) 1629 WP_001186608.1 recombinase family protein Machinery gene
  NYF25_RS00220 (NYF25_00220) ccrA 47617..48966 (-) 1350 WP_000815648.1 recombinase family protein Machinery gene
  NYF25_RS00225 (NYF25_00225) - 49200..50987 (-) 1788 WP_031880882.1 DUF927 domain-containing protein -
  NYF25_RS00230 (NYF25_00230) - 51107..52537 (-) 1431 WP_031880883.1 DUF6038 family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52681.37 Da        Isoelectric Point: 9.9639

>NTDB_id=725967 NYF25_RS00220 WP_000815648.1 47617..48966(-) (ccrA) [Staphylococcus aureus strain NRL 02/947]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=725967 NYF25_RS00220 WP_000815648.1 47617..48966(-) (ccrA) [Staphylococcus aureus strain NRL 02/947]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.773

100

0.978
  ccrA Staphylococcus aureus COL

75.724

100

0.757