Detailed information NTG0072302

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EKM74_RS03510
• Genome accession: NZ_AP019306
• Coordinates: 639181..640224 (-)
• Length: 347 a.a.
• NCBI ID: WP_125571277.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain TUM9463
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 634181..645224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EKM74_RS03480	-	634602..635858 (-)	1257	WP_125571275.1	aminopeptidase	-
EKM74_RS03485	-	635861..636061 (-)	201	WP_000180460.1	DUF1128 family protein	-
EKM74_RS03490	-	636208..636672 (+)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
EKM74_RS03495	-	636679..636954 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EKM74_RS03500	-	637232..638449 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
EKM74_RS03505	vraR	638562..639191 (-)	630	WP_042109421.1	two-component system response regulator VraR	Regulator
EKM74_RS03510	vraS	639181..640224 (-)	1044	WP_125571277.1	sensor histidine kinase	Regulator
EKM74_RS03515	liaF	640221..640922 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
EKM74_RS03520	-	640937..641323 (-)	387	WP_001110179.1	hypothetical protein	-
EKM74_RS03525	map	641540..642298 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EKM74_RS03535	-	642829..643815 (+)	987	WP_000999717.1	FUSC family protein	-
EKM74_RS03545	-	644246..644659 (-)	414	WP_001557448.1	hypothetical protein	-
EKM74_RS03550	-	644688..644798 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40026.49 Da
• Isoelectric Point: 6.0577

>NTDB_id=72302 EKM74_RS03510 WP_125571277.1 639181..640224(-) (vraS) [Staphylococcus aureus strain TUM9463]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPIKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=72302 EKM74_RS03510 WP_125571277.1 639181..640224(-) (vraS) [Staphylococcus aureus strain TUM9463]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATAAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997