Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EKM72_RS13155 Genome accession   NZ_AP019305
Coordinates   2472361..2473347 (+) Length   328 a.a.
NCBI ID   WP_000959282.1    Uniprot ID   A0A7U7EXT8
Organism   Staphylococcus aureus strain TUM9458     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 2467361..2478347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM72_RS13130 opp4B 2467575..2468537 (+) 963 WP_000915997.1 oligopeptide ABC transporter permease -
  EKM72_RS13135 opp4C 2468549..2469430 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  EKM72_RS13140 trpS 2469472..2470461 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  EKM72_RS13145 spxA 2470755..2471150 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  EKM72_RS13150 mecA 2471521..2472240 (+) 720 WP_001217728.1 adaptor protein MecA -
  EKM72_RS13155 coiA 2472361..2473347 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  EKM72_RS13160 pepF 2473395..2475203 (+) 1809 WP_000082725.1 oligoendopeptidase F -
  EKM72_RS13165 yjbH 2475663..2476469 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  EKM72_RS13170 - 2476492..2476857 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  EKM72_RS13175 - 2476961..2477554 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  EKM72_RS13180 - 2477740..2478087 (+) 348 WP_001242103.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38878.55 Da        Isoelectric Point: 9.5714

>NTDB_id=72278 EKM72_RS13155 WP_000959282.1 2472361..2473347(+) (coiA) [Staphylococcus aureus strain TUM9458]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=72278 EKM72_RS13155 WP_000959282.1 2472361..2473347(+) (coiA) [Staphylococcus aureus strain TUM9458]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

100

100

1
  coiA Staphylococcus aureus MW2

97.561

100

0.976

Multiple sequence alignment