Detailed information NTG0722689

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NX856_RS18630
• Genome accession: NZ_CP103412
• Coordinates: 3663429..3664592 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HF-14109
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3658429..3669592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX856_RS18600 (NX856_18600)	-	3658693..3659112 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
NX856_RS18605 (NX856_18605)	comFC	3659186..3659875 (-)	690	WP_199022660.1	phosphoribosyltransferase family protein	Machinery gene
NX856_RS18610 (NX856_18610)	-	3659881..3660165 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
NX856_RS18615 (NX856_18615)	comFA	3660223..3661608 (-)	1386	WP_124692700.1	DEAD/DEAH box helicase	Machinery gene
NX856_RS18620 (NX856_18620)	-	3661717..3662565 (-)	849	WP_003151387.1	DegV family protein	-
NX856_RS18625 (NX856_18625)	degU	3662663..3663352 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NX856_RS18630 (NX856_18630)	degS	3663429..3664592 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NX856_RS18635 (NX856_18635)	-	3664815..3665462 (+)	648	WP_007614107.1	YigZ family protein	-
NX856_RS18640 (NX856_18640)	-	3665467..3666687 (+)	1221	WP_007407486.1	LCP family protein	-
NX856_RS18645 (NX856_18645)	-	3666786..3667862 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NX856_RS18650 (NX856_18650)	-	3667995..3669191 (-)	1197	WP_218791395.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=722689 NX856_RS18630 WP_007407484.1 3663429..3664592(-) (degS) [Bacillus velezensis strain HF-14109]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=722689 NX856_RS18630 WP_007407484.1 3663429..3664592(-) (degS) [Bacillus velezensis strain HF-14109]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951