Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NX856_RS05920 Genome accession   NZ_CP103412
Coordinates   1138806..1139462 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain HF-14109     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1133806..1144462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX856_RS05890 (NX856_05890) oppF 1134335..1135252 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NX856_RS05895 (NX856_05895) - 1135359..1136546 (+) 1188 WP_032866147.1 putative glycoside hydrolase -
  NX856_RS05900 (NX856_05900) - 1136664..1137242 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NX856_RS05905 (NX856_05905) spx 1137421..1137816 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NX856_RS05910 (NX856_05910) - 1137874..1138530 (-) 657 WP_032866146.1 TerC family protein -
  NX856_RS05915 (NX856_05915) - 1138713..1138823 (+) 111 Protein_1105 adaptor protein MecA -
  NX856_RS05920 (NX856_05920) mecA 1138806..1139462 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NX856_RS05925 (NX856_05925) - 1139613..1140773 (+) 1161 WP_032866145.1 competence protein CoiA family protein -
  NX856_RS05930 (NX856_05930) pepF 1141001..1142830 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  NX856_RS05935 (NX856_05935) - 1142868..1143035 (-) 168 WP_003155026.1 hypothetical protein -
  NX856_RS05940 (NX856_05940) spxH 1143321..1144223 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=722647 NX856_RS05920 WP_003155032.1 1138806..1139462(+) (mecA) [Bacillus velezensis strain HF-14109]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=722647 NX856_RS05920 WP_003155032.1 1138806..1139462(+) (mecA) [Bacillus velezensis strain HF-14109]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895