Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   PWK66_RS04335 Genome accession   NZ_CP118482
Coordinates   819014..819490 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain 20160179     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 814014..824490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWK66_RS04300 (PWK66_04250) - 814084..814245 (+) 162 WP_002987333.1 hypothetical protein -
  PWK66_RS04305 (PWK66_04255) - 814248..814859 (+) 612 WP_002990014.1 DUF1366 domain-containing protein -
  PWK66_RS04310 (PWK66_04260) - 814870..815166 (+) 297 WP_002990012.1 hypothetical protein -
  PWK66_RS04315 (PWK66_04265) - 815163..815348 (+) 186 WP_002990010.1 holin -
  PWK66_RS04320 (PWK66_04270) - 815434..816723 (+) 1290 WP_044565069.1 GH25 family lysozyme -
  PWK66_RS04325 (PWK66_04275) spei 816997..817674 (+) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  PWK66_RS04330 (PWK66_04280) speh 817700..818410 (+) 711 WP_002990004.1 streptococcal pyrogenic exotoxin SpeH -
  PWK66_RS04335 (PWK66_04285) mutX 819014..819490 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  PWK66_RS04340 (PWK66_04290) - 819548..820729 (+) 1182 WP_002990002.1 AI-2E family transporter -
  PWK66_RS04345 (PWK66_04295) - 820719..821966 (+) 1248 WP_002990000.1 tetratricopeptide repeat protein -
  PWK66_RS04350 (PWK66_04300) fbp54 822025..823677 (-) 1653 WP_002989998.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=722569 PWK66_RS04335 WP_002984880.1 819014..819490(+) (mutX) [Streptococcus pyogenes strain 20160179]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=722569 PWK66_RS04335 WP_002984880.1 819014..819490(+) (mutX) [Streptococcus pyogenes strain 20160179]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703