NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	NX819_RS18105	Genome accession	NZ_CP103351
Coordinates	3480291..3480884 (+)	Length	197 a.a.
NCBI ID	WP_003228214.1	Uniprot ID	A0A199WEF2
Organism	Bacillus subtilis strain SRCM115947
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3475291..3485884

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX819_RS18075 (NX819_18075)	psmA	3475545..3475880 (+)	336	WP_003242480.1	SMR family transporter	-
NX819_RS18080 (NX819_18080)	psmB	3475880..3476200 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
NX819_RS18085 (NX819_18085)	yvdQ	3476236..3476748 (-)	513	WP_003243249.1	DUF3231 family protein	-
NX819_RS18090 (NX819_18090)	cotNP	3477000..3478343 (-)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
NX819_RS18095 (NX819_18095)	cotR	3478699..3479661 (+)	963	WP_003243674.1	sporulation hydrolase CotR	-
NX819_RS18105 (NX819_18105)	clpP	3480291..3480884 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
NX819_RS18110 (NX819_18110)	pgmB	3480930..3481610 (-)	681	WP_003228210.1	beta-phosphoglucomutase	-
NX819_RS18115 (NX819_18115)	malL	3481607..3483292 (-)	1686	WP_003243333.1	oligo-1,6-glucosidase	-
NX819_RS18120 (NX819_18120)	mdxK	3483285..3485558 (-)	2274	WP_019712404.1	maltose phosphorylase	-

Sequence

Protein

Download Length: 197 a.a. Molecular weight: 21682.00 Da Isoelectric Point: 4.9416

                                >NTDB_id=722245 NX819_RS18105 WP_003228214.1 3480291..3480884(+) (clpP) [Bacillus subtilis strain SRCM115947]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ

PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

Download Length: 594 bp

                                >NTDB_id=722245 NX819_RS18105 WP_003228214.1 3480291..3480884(+) (clpP) [Bacillus subtilis strain SRCM115947]

ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA

TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG

AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC

ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG

CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA

CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG

CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA

CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538

Detailed information NTG0722245