Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EL334_RS11525 Genome accession   NZ_AP019192
Coordinates   2123110..2123772 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain ASP0581     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2118110..2128772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL334_RS11500 (ASP0581_21240) - 2118260..2118526 (-) 267 WP_001278167.1 Veg family protein -
  EL334_RS11505 (ASP0581_21250) dnaB 2118528..2119880 (-) 1353 WP_000852486.1 replicative DNA helicase -
  EL334_RS11510 (ASP0581_21260) rplI 2119924..2120376 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EL334_RS11515 (ASP0581_21270) - 2120373..2122346 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  EL334_RS11520 (ASP0581_21280) hpf 2122482..2123030 (-) 549 WP_033705088.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL334_RS11525 (ASP0581_21290) comFC/cflB 2123110..2123772 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  EL334_RS11530 (ASP0581_21300) comFA/cflA 2123769..2125067 (-) 1299 WP_000867590.1 DEAD/DEAH box helicase Machinery gene
  EL334_RS11535 (ASP0581_21310) - 2125123..2125758 (+) 636 WP_000395739.1 YigZ family protein -
  EL334_RS11540 (ASP0581_21320) cysK 2126043..2126963 (+) 921 WP_033705087.1 cysteine synthase A -
  EL334_RS11550 (ASP0581_21330) - 2127038..2127576 (-) 539 Protein_2127 IS66 family transposase -
  EL334_RS11555 - 2127549..2127857 (+) 309 Protein_2128 transposase -
  EL334_RS11560 (ASP0581_21350) tnpB 2127880..2128230 (-) 351 WP_033705086.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=72180 EL334_RS11525 WP_000649971.1 2123110..2123772(-) (comFC/cflB) [Streptococcus pneumoniae strain ASP0581]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=72180 EL334_RS11525 WP_000649971.1 2123110..2123772(-) (comFC/cflB) [Streptococcus pneumoniae strain ASP0581]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment