Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   PVK49_RS05135 Genome accession   NZ_CP118306
Coordinates   1026439..1026915 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain 20154608     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1021439..1031915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK49_RS05120 (PVK49_05115) fbp54 1022252..1023904 (+) 1653 WP_047235843.1 Rqc2 family fibronectin-binding protein Fbp54 -
  PVK49_RS05125 (PVK49_05120) - 1023963..1025210 (-) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  PVK49_RS05130 (PVK49_05125) - 1025200..1026381 (-) 1182 WP_002984879.1 AI-2E family transporter -
  PVK49_RS05135 (PVK49_05130) mutX 1026439..1026915 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  PVK49_RS05140 (PVK49_05135) speh 1027519..1028229 (-) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  PVK49_RS05145 (PVK49_05140) spei 1028255..1028932 (-) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  PVK49_RS05150 (PVK49_05145) - 1029206..1030540 (-) 1335 WP_011284838.1 GH25 family lysozyme -
  PVK49_RS05155 (PVK49_05150) - 1030652..1030837 (-) 186 WP_002990010.1 holin -
  PVK49_RS05160 (PVK49_05155) - 1030834..1031130 (-) 297 WP_002990012.1 hypothetical protein -
  PVK49_RS05165 (PVK49_05160) - 1031140..1031751 (-) 612 WP_047235844.1 DUF1366 domain-containing protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=721653 PVK49_RS05135 WP_002984880.1 1026439..1026915(-) (mutX) [Streptococcus pyogenes strain 20154608]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=721653 PVK49_RS05135 WP_002984880.1 1026439..1026915(-) (mutX) [Streptococcus pyogenes strain 20154608]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703