Detailed information NTG0721378

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: MGCS35922_RS10545
• Genome accession: NZ_CP118097
• Coordinates: 2146276..2148831 (-)
• Length: 851 a.a.
• NCBI ID: WP_012767643.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2141276..2153831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS35922_RS10520 (MGCS35922_04288)	-	2141402..2141755 (-)	354	WP_003058738.1	VOC family protein	-
MGCS35922_RS10525 (MGCS35922_04290)	-	2141758..2142330 (-)	573	WP_003058799.1	DNA-3-methyladenine glycosylase I	-
MGCS35922_RS10530 (MGCS35922_04292)	ruvA	2142340..2142933 (-)	594	WP_003058778.1	Holliday junction branch migration protein RuvA	Machinery gene
MGCS35922_RS10535 (MGCS35922_04294)	-	2142935..2144155 (-)	1221	WP_084916281.1	MFS transporter	-
MGCS35922_RS10540 (MGCS35922_04296)	hexB	2144166..2146148 (-)	1983	WP_012767642.1	DNA mismatch repair endonuclease MutL	Machinery gene
MGCS35922_RS10545 (MGCS35922_04298)	hexA	2146276..2148831 (-)	2556	WP_012767643.1	DNA mismatch repair protein MutS	Machinery gene
MGCS35922_RS10550 (MGCS35922_04300)	-	2148818..2149171 (-)	354	WP_012767644.1	YlbF family regulator	-
MGCS35922_RS10555 (MGCS35922_04302)	argR	2149168..2149605 (-)	438	WP_003055516.1	arginine repressor	-
MGCS35922_RS10560 (MGCS35922_04304)	argS	2149894..2151585 (+)	1692	WP_015017500.1	arginine--tRNA ligase	-
MGCS35922_RS10565 (MGCS35922_04306)	-	2151655..2153052 (-)	1398	WP_014612639.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95288.71 Da
• Isoelectric Point: 4.8790

>NTDB_id=721378 MGCS35922_RS10545 WP_012767643.1 2146276..2148831(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSAYVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAAVAETNHYIRPQFN
DNHVIKIQEGRHAVVEKVMGVQEYIPNSISFNQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPSKV
EPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=721378 MGCS35922_RS10545 WP_012767643.1 2146276..2148831(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAAGCAGCACAACTCTTAGAAATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGCGTGCCACATCATTCTGCCCAACAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATCACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGTCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTCTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTGTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGCCGTGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCCATATTAGAGTCTTTTAACA
GCGCTTATGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCATGTTACGAATTCAAATCTTAGCTTAGTTCCCGACCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGCCGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTAAAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTAACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGCGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATTATGGCCCAGATGGGCTCATTTGTAGCTGCTGACCATGTTGATTTGCCTCTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGAGCCAGTGACAATTCCCTTATTCTATTTGATGAACTAGGGAGGGGTACGGCAACTTATGATGGTATGG
CACTGGCTCAGGCAATTATCGAATATATCCATGATAGAGTTGGTGCTAAGACCATGTTTGCAACGCACTATCATGAGTTG
ACAGACTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTAACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTAGCAAAAATAGCAGGACTTCCTGAGGCCCTGC
TAAGCAGAGCAGATGAGGTGCTTACGCGTTTAGAAGCGCAAGCACAATCTGCTGAGATAATATCAGTCCCTTCAAAAGTT
GAGCCAAGCAGCGCTGCTAGAGAGGGACAGTTATCGCTGTTTCCTGATGAGGATAAGTCTCAGGAGATTATTCACACGTT
AGAAGCTATTGATGTGATGAACATGACTCCACTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	70.975	100	0.71
mutS	Pseudomonas stutzeri strain ATCC 17587	36.842	100	0.37