Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ST1232TP_RS03740 Genome accession   NZ_AP024311
Coordinates   799220..801205 (+) Length   661 a.a.
NCBI ID   WP_103146233.1    Uniprot ID   -
Organism   Staphylococcus aureus strain THI2018-120     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 794220..806205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST1232TP_RS03715 - 795065..795184 (+) 120 WP_031774844.1 hypothetical protein -
  ST1232TP_RS03720 (THI2018120TP_07040) prfB 795339..796449 (+) 1111 WP_010956549.1 peptide chain release factor 2 -
  ST1232TP_RS03725 (THI2018120TP_07050) - 797055..797894 (+) 840 WP_000749384.1 CHAP domain-containing protein -
  ST1232TP_RS03730 (THI2018120TP_07060) - 798068..798718 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  ST1232TP_RS03735 (THI2018120TP_07070) - 798715..798951 (+) 237 WP_000638419.1 CsbA family protein -
  ST1232TP_RS03740 (THI2018120TP_07080) uvrB 799220..801205 (+) 1986 WP_103146233.1 excinuclease ABC subunit UvrB Machinery gene
  ST1232TP_RS03745 (THI2018120TP_07090) uvrA 801213..804059 (+) 2847 WP_000662684.1 excinuclease ABC subunit UvrA Machinery gene
  ST1232TP_RS03750 (THI2018120TP_07100) hprK 804669..805601 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76662.36 Da        Isoelectric Point: 5.0538

>NTDB_id=72135 ST1232TP_RS03740 WP_103146233.1 799220..801205(+) (uvrB) [Staphylococcus aureus strain THI2018-120]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRIEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=72135 ST1232TP_RS03740 WP_103146233.1 799220..801205(+) (uvrB) [Staphylococcus aureus strain THI2018-120]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGAAAACCAACATTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGCGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGATTGAGTTTTTCGGTGATGAGATTGACCGAATTCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTGCCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(434-546)

UvrB interaction domain (UvrB_inter)

(161-251)

Ultra-violet resistance protein B (UvrB)

(553-594)

Type III restriction enzyme, res subunit (ResIII)

(14-140)

UvrB/uvrC motif (UVR)

(626-659)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.381

98.79

0.666
  uvrB Streptococcus pneumoniae D39

67.381

98.79

0.666
  uvrB Streptococcus pneumoniae TIGR4

67.381

98.79

0.666

Multiple sequence alignment