Detailed information NTG0072132

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL334_RS04770
• Genome accession: NZ_AP019192
• Coordinates: 891323..893563 (+)
• Length: 746 a.a.
• NCBI ID: WP_033705318.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ASP0581
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 886323..898563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL334_RS04725 (ASP0581_08910)	-	886474..887442 (+)	969	WP_000658183.1	PhoH family protein	-
EL334_RS04735 (ASP0581_08920)	-	887635..888135 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EL334_RS04740	-	888138..888463 (+)	326	Protein_893	TfoX/Sxy family protein	-
EL334_RS12220	ald	888764..889875 (-)	1112	Protein_894	alanine dehydrogenase	-
EL334_RS04760 (ASP0581_08970)	-	890052..890621 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
EL334_RS04765 (ASP0581_08980)	comEA/celA/cilE	890689..891339 (+)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL334_RS04770 (ASP0581_08990)	comEC/celB	891323..893563 (+)	2241	WP_033705318.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL334_RS04775 (ASP0581_09000)	-	893705..893929 (+)	225	WP_015898758.1	hypothetical protein	-
EL334_RS04780 (ASP0581_09010)	-	893961..894548 (+)	588	WP_000933540.1	ATP-binding cassette domain-containing protein	-
EL334_RS04785 (ASP0581_09020)	-	894552..895730 (+)	1179	WP_033705319.1	membrane protein	-
EL334_RS04790 (ASP0581_09030)	infC	896041..896571 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
EL334_RS04795 (ASP0581_09040)	rpmI	896604..896804 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
EL334_RS04800 (ASP0581_09050)	rplT	896856..897215 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
EL334_RS04805 (ASP0581_09060)	-	897273..897653 (+)	381	WP_033705321.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84448.87 Da
• Isoelectric Point: 9.3992

>NTDB_id=72132 EL334_RS04770 WP_033705318.1 891323..893563(+) (comEC/celB) [Streptococcus pneumoniae strain ASP0581]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASSPLVFGQPNEWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKTTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPREIGYGGHEDSLVLYGKL
LNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=72132 EL334_RS04770 WP_033705318.1 891323..893563(+) (comEC/celB) [Streptococcus pneumoniae strain ASP0581]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCGAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGCTTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGGCAAGTAGTCCTCTAGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGACGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGCAGAACTACAGGTGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGTACTTGCCCATTTTCG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGGAAATTGGATATGGAGGTCATGAAGATTCCCTGGTTCTTTATGGGAAACTC
TTGAATAATCACTTTCTCTTCATAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGTACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGCTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-630)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	96.649	100	0.966
comEC/celB	Streptococcus pneumoniae Rx1	95.174	100	0.952
comEC/celB	Streptococcus pneumoniae D39	95.174	100	0.952
comEC/celB	Streptococcus pneumoniae R6	95.174	100	0.952
comEC/celB	Streptococcus mitis NCTC 12261	92.081	99.866	0.92
comEC/celB	Streptococcus mitis SK321	91.957	100	0.92
comEC	Lactococcus lactis subsp. cremoris KW2	44.399	99.33	0.441