Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   NW953_RS07615 Genome accession   NZ_CP102975
Coordinates   1593360..1594334 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain 16CS0209     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1588360..1599334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW953_RS07575 (NW953_07575) gcvT 1588861..1589952 (-) 1092 WP_258409151.1 glycine cleavage system aminomethyltransferase GcvT -
  NW953_RS07580 (NW953_07580) - 1590111..1590635 (-) 525 WP_001015122.1 shikimate kinase -
  NW953_RS07585 (NW953_07585) - 1590625..1590771 (-) 147 WP_001789879.1 hypothetical protein -
  NW953_RS07590 (NW953_07590) comGF 1590868..1591365 (-) 498 WP_001796472.1 competence type IV pilus minor pilin ComGF Machinery gene
  NW953_RS07595 (NW953_07595) comGE 1591283..1591582 (-) 300 WP_000844410.1 hypothetical protein Machinery gene
  NW953_RS07600 (NW953_07600) comGD 1591569..1592015 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  NW953_RS07605 (NW953_07605) comGC 1591993..1592304 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  NW953_RS07610 (NW953_07610) comGB 1592318..1593388 (-) 1071 WP_258409152.1 competence type IV pilus assembly protein ComGB Machinery gene
  NW953_RS07615 (NW953_07615) comGA 1593360..1594334 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  NW953_RS07620 (NW953_07620) - 1594386..1595009 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  NW953_RS07625 (NW953_07625) - 1595006..1595335 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  NW953_RS07630 (NW953_07630) - 1595335..1596321 (-) 987 WP_000161315.1 ROK family glucokinase -
  NW953_RS07635 (NW953_07635) - 1596318..1596521 (-) 204 WP_000087561.1 YqgQ family protein -
  NW953_RS07640 (NW953_07640) - 1596502..1597965 (-) 1464 WP_258409153.1 rhomboid family intramembrane serine protease -
  NW953_RS07645 (NW953_07645) - 1597977..1598516 (-) 540 WP_258409154.1 5-formyltetrahydrofolate cyclo-ligase -
  NW953_RS07650 (NW953_07650) rpmG 1598725..1598874 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=721001 NW953_RS07615 WP_000697220.1 1593360..1594334(-) (comGA) [Staphylococcus aureus strain 16CS0209]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=721001 NW953_RS07615 WP_000697220.1 1593360..1594334(-) (comGA) [Staphylococcus aureus strain 16CS0209]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCAATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGACTTGATGTATCTACACAACAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAAATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATAATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGTTATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1