Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW963_RS10160 Genome accession   NZ_CP102972
Coordinates   2057144..2057860 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 05-RR-90     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2052144..2062860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW963_RS10130 (NW963_10125) - 2052359..2052985 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW963_RS10135 (NW963_10130) - 2053346..2054131 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  NW963_RS10140 (NW963_10135) - 2054731..2054865 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW963_RS10145 (NW963_10140) - 2055101..2055664 (+) 564 WP_258412239.1 accessory gene regulator AgrB -
  NW963_RS10150 (NW963_10145) agrD 2055668..2055808 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  NW963_RS10155 (NW963_10150) agrC 2055833..2057125 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  NW963_RS10160 (NW963_10155) agrA 2057144..2057860 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  NW963_RS10165 (NW963_10160) - 2057932..2058041 (+) 110 Protein_1964 hypothetical protein -
  NW963_RS10170 (NW963_10165) - 2058229..2059188 (-) 960 WP_001253312.1 carbohydrate kinase -
  NW963_RS10175 (NW963_10170) - 2059185..2060669 (-) 1485 WP_258412240.1 glycoside hydrolase family 32 protein -
  NW963_RS10180 (NW963_10175) - 2060818..2061768 (-) 951 WP_043044119.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=720929 NW963_RS10160 WP_000688492.1 2057144..2057860(+) (agrA) [Staphylococcus aureus strain 05-RR-90]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720929 NW963_RS10160 WP_000688492.1 2057144..2057860(+) (agrA) [Staphylococcus aureus strain 05-RR-90]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1