Detailed information NTG0720886

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW975_RS09435
• Genome accession: NZ_CP102971
• Coordinates: 1934883..1935926 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 08-G-E
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1929883..1940926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW975_RS09405 (NW975_09405)	-	1930305..1931561 (-)	1257	WP_001793428.1	aminopeptidase	-
NW975_RS09410 (NW975_09410)	-	1931564..1931764 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW975_RS09415 (NW975_09415)	-	1931911..1932375 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW975_RS09420 (NW975_09420)	-	1932382..1932657 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW975_RS09425 (NW975_09425)	-	1932935..1934152 (+)	1218	WP_179330255.1	YihY/virulence factor BrkB family protein	-
NW975_RS09430 (NW975_09430)	vraR	1934264..1934893 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NW975_RS09435 (NW975_09435)	vraS	1934883..1935926 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW975_RS09440 (NW975_09440)	liaF	1935923..1936624 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW975_RS09445 (NW975_09445)	-	1936639..1937025 (-)	387	WP_258414722.1	hypothetical protein	-
NW975_RS09450 (NW975_09450)	map	1937242..1938000 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW975_RS09455 (NW975_09455)	-	1938531..1939517 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW975_RS09460 (NW975_09460)	-	1940007..1940420 (-)	414	WP_258414837.1	hypothetical protein	-
NW975_RS09465 (NW975_09465)	-	1940449..1940559 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720886 NW975_RS09435 WP_001017131.1 1934883..1935926(-) (vraS) [Staphylococcus aureus strain 08-G-E]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720886 NW975_RS09435 WP_001017131.1 1934883..1935926(-) (vraS) [Staphylococcus aureus strain 08-G-E]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1