Detailed information NTG0720844

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW983_RS09475
• Genome accession: NZ_CP102970
• Coordinates: 1940104..1941147 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 09-G-F
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1935104..1946147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW983_RS09445 (NW983_09445)	-	1935526..1936782 (-)	1257	WP_001793428.1	aminopeptidase	-
NW983_RS09450 (NW983_09450)	-	1936785..1936985 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW983_RS09455 (NW983_09455)	-	1937132..1937596 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW983_RS09460 (NW983_09460)	-	1937603..1937878 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW983_RS09465 (NW983_09465)	-	1938156..1939373 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
NW983_RS09470 (NW983_09470)	vraR	1939485..1940114 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW983_RS09475 (NW983_09475)	vraS	1940104..1941147 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW983_RS09480 (NW983_09480)	liaF	1941144..1941845 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW983_RS09485 (NW983_09485)	-	1941860..1942246 (-)	387	WP_001110179.1	hypothetical protein	-
NW983_RS09490 (NW983_09490)	map	1942463..1943221 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW983_RS09495 (NW983_09495)	-	1943924..1944910 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW983_RS09500 (NW983_09500)	-	1945341..1945754 (-)	414	WP_258412090.1	hypothetical protein	-
NW983_RS09505 (NW983_09505)	-	1945783..1945893 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720844 NW983_RS09475 WP_001017131.1 1940104..1941147(-) (vraS) [Staphylococcus aureus strain 09-G-F]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720844 NW983_RS09475 WP_001017131.1 1940104..1941147(-) (vraS) [Staphylococcus aureus strain 09-G-F]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1