Detailed information NTG0720764

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW947_RS09535
• Genome accession: NZ_CP102967
• Coordinates: 1943956..1944999 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 17-H-61
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1938956..1949999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW947_RS09505 (NW947_09505)	-	1939374..1940630 (-)	1257	WP_258416250.1	aminopeptidase	-
NW947_RS09510 (NW947_09510)	-	1940633..1940833 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW947_RS09515 (NW947_09515)	-	1940980..1941444 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW947_RS09520 (NW947_09520)	-	1941451..1941726 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW947_RS09525 (NW947_09525)	-	1942004..1943221 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
NW947_RS09530 (NW947_09530)	vraR	1943337..1943966 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW947_RS09535 (NW947_09535)	vraS	1943956..1944999 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW947_RS09540 (NW947_09540)	liaF	1944996..1945697 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW947_RS09545 (NW947_09545)	-	1945712..1946098 (-)	387	WP_001110179.1	hypothetical protein	-
NW947_RS09550 (NW947_09550)	map	1946315..1947073 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW947_RS09555 (NW947_09555)	-	1947543..1948529 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW947_RS09560 (NW947_09560)	-	1948960..1949373 (-)	414	WP_001549145.1	hypothetical protein	-
NW947_RS09565 (NW947_09565)	-	1949402..1949512 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720764 NW947_RS09535 WP_001017131.1 1943956..1944999(-) (vraS) [Staphylococcus aureus strain 17-H-61]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720764 NW947_RS09535 WP_001017131.1 1943956..1944999(-) (vraS) [Staphylococcus aureus strain 17-H-61]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1