Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW941_RS10170 Genome accession   NZ_CP102963
Coordinates   2058594..2059310 (+) Length   238 a.a.
NCBI ID   WP_258415052.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 40-B-50     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2053594..2064310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW941_RS10140 (NW941_10175) - 2053812..2054438 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW941_RS10145 (NW941_10180) - 2054799..2055584 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NW941_RS10150 (NW941_10185) - 2056181..2056315 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW941_RS10155 (NW941_10190) - 2056551..2057114 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  NW941_RS10160 (NW941_10195) agrD 2057118..2057258 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  NW941_RS10165 (NW941_10200) agrC 2057283..2058575 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  NW941_RS10170 (NW941_10205) agrA 2058594..2059310 (+) 717 WP_258415052.1 quorum-sensing response regulator AgrA Regulator
  NW941_RS10175 (NW941_10210) - 2059382..2059491 (+) 110 Protein_1964 hypothetical protein -
  NW941_RS10180 (NW941_10215) - 2059679..2060638 (-) 960 WP_001253302.1 carbohydrate kinase -
  NW941_RS10185 (NW941_10220) - 2060635..2062119 (-) 1485 WP_000141413.1 glycoside hydrolase family 32 protein -
  NW941_RS10190 (NW941_10225) - 2062268..2063218 (-) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27921.90 Da        Isoelectric Point: 6.0926

>NTDB_id=720681 NW941_RS10170 WP_258415052.1 2058594..2059310(+) (agrA) [Staphylococcus aureus strain 40-B-50]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTYVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720681 NW941_RS10170 WP_258415052.1 2058594..2059310(+) (agrA) [Staphylococcus aureus strain 40-B-50]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACGTATGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996