Detailed information NTG0720644

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW971_RS13610
• Genome accession: NZ_CP102962
• Coordinates: 2718986..2719873 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 16CS0212
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713986..2724873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW971_RS13580 (NW971_13580)	-	2713995..2714087 (+)	93	WP_010956583.1	hypothetical protein	-
NW971_RS13585 (NW971_13585)	-	2714195..2714692 (-)	498	WP_001065267.1	glutathione peroxidase	-
NW971_RS13590 (NW971_13590)	-	2714702..2714962 (-)	261	WP_078056482.1	hypothetical protein	-
NW971_RS13595 (NW971_13595)	-	2715344..2715457 (-)	114	WP_072357681.1	hypothetical protein	-
NW971_RS13600 (NW971_13600)	-	2716126..2718126 (-)	2001	WP_258464563.1	ABC transporter permease	-
NW971_RS13605 (NW971_13605)	-	2718123..2718878 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
NW971_RS13610 (NW971_13610)	braS	2718986..2719873 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW971_RS13615 (NW971_13615)	braR	2719884..2720549 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW971_RS13620 (NW971_13620)	-	2720575..2720775 (-)	201	WP_000604725.1	hypothetical protein	-
NW971_RS13625 (NW971_13625)	-	2720973..2722397 (+)	1425	WP_258464564.1	alkaline phosphatase	-
NW971_RS14085	-	2722456..2722557 (-)	102	WP_000731976.1	SE2200 family small protein	-
NW971_RS13635 (NW971_13635)	-	2722679..2723134 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW971_RS13640 (NW971_13640)	-	2723379..2724140 (-)	762	WP_258464566.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=720644 NW971_RS13610 WP_000143420.1 2718986..2719873(-) (braS) [Staphylococcus aureus strain 16CS0212]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720644 NW971_RS13610 WP_000143420.1 2718986..2719873(-) (braS) [Staphylococcus aureus strain 16CS0212]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCTATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993