Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW971_RS10460 Genome accession   NZ_CP102962
Coordinates   2096265..2096981 (+) Length   238 a.a.
NCBI ID   WP_258464401.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 16CS0212     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2091265..2101981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW971_RS10430 (NW971_10430) - 2091480..2092106 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW971_RS10435 (NW971_10435) - 2092468..2093253 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  NW971_RS10440 (NW971_10440) hld 2093852..2093932 (-) 81 WP_000046022.1 delta-hemolysin -
  NW971_RS10445 (NW971_10445) agrB 2094223..2094792 (+) 570 WP_086153163.1 accessory gene regulator AgrB -
  NW971_RS10450 (NW971_10450) agrD 2094789..2094929 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NW971_RS10455 (NW971_10455) agrC 2094954..2096246 (+) 1293 WP_031844950.1 quorum-sensing sensor histidine kinase AgrC -
  NW971_RS10460 (NW971_10460) agrA 2096265..2096981 (+) 717 WP_258464401.1 quorum-sensing response regulator AgrA Regulator
  NW971_RS10465 (NW971_10465) - 2097053..2097160 (+) 108 WP_041204320.1 hypothetical protein -
  NW971_RS10470 (NW971_10470) - 2097348..2098307 (-) 960 WP_258464402.1 carbohydrate kinase -
  NW971_RS10475 (NW971_10475) - 2098304..2099788 (-) 1485 WP_258464403.1 sucrose-6-phosphate hydrolase -
  NW971_RS10480 (NW971_10480) - 2099937..2100887 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.96 Da        Isoelectric Point: 6.4949

>NTDB_id=720640 NW971_RS10460 WP_258464401.1 2096265..2096981(+) (agrA) [Staphylococcus aureus strain 16CS0212]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSKLTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720640 NW971_RS10460 WP_258464401.1 2096265..2096981(+) (agrA) [Staphylococcus aureus strain 16CS0212]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTAAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996