Detailed information NTG0720602

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW973_RS13405
• Genome accession: NZ_CP102961
• Coordinates: 2694942..2695829 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 03-RR-88
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2689942..2700829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW973_RS13375 (NW973_13375)	-	2689961..2690053 (+)	93	WP_010956583.1	hypothetical protein	-
NW973_RS13380 (NW973_13380)	-	2690161..2690658 (-)	498	WP_153159376.1	glutathione peroxidase	-
NW973_RS13385 (NW973_13385)	-	2690668..2690928 (-)	261	WP_001791974.1	hypothetical protein	-
NW973_RS13390 (NW973_13390)	-	2691310..2691423 (-)	114	WP_072384844.1	hypothetical protein	-
NW973_RS13395 (NW973_13395)	-	2692082..2694082 (-)	2001	WP_258410878.1	ABC transporter permease	-
NW973_RS13400 (NW973_13400)	-	2694079..2694834 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NW973_RS13405 (NW973_13405)	braS	2694942..2695829 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW973_RS13410 (NW973_13410)	braR	2695840..2696505 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW973_RS13415 (NW973_13415)	-	2696531..2696731 (-)	201	WP_000604727.1	hypothetical protein	-
NW973_RS13420 (NW973_13420)	-	2696929..2698353 (+)	1425	WP_000953744.1	alkaline phosphatase	-
NW973_RS13870	-	2698413..2698514 (-)	102	WP_000731972.1	SE2200 family small protein	-
NW973_RS13430 (NW973_13430)	-	2698636..2699091 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW973_RS13435 (NW973_13435)	-	2699336..2700097 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=720602 NW973_RS13405 WP_000143419.1 2694942..2695829(-) (braS) [Staphylococcus aureus strain 03-RR-88]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720602 NW973_RS13405 WP_000143419.1 2694942..2695829(-) (braS) [Staphylococcus aureus strain 03-RR-88]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997