Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW973_RS10270 Genome accession   NZ_CP102961
Coordinates   2076882..2077598 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 03-RR-88     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071882..2082598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW973_RS10240 (NW973_10240) - 2072102..2072728 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW973_RS10245 (NW973_10245) - 2073089..2073874 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NW973_RS10250 (NW973_10250) - 2074471..2074605 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW973_RS10255 (NW973_10255) - 2074841..2075404 (+) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  NW973_RS10260 (NW973_10260) agrD 2075407..2075550 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  NW973_RS10265 (NW973_10265) agrC 2075580..2076863 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  NW973_RS10270 (NW973_10270) agrA 2076882..2077598 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NW973_RS10275 (NW973_10275) - 2077670..2077779 (+) 110 Protein_1987 hypothetical protein -
  NW973_RS10280 (NW973_10280) - 2077967..2078926 (-) 960 WP_258410763.1 carbohydrate kinase -
  NW973_RS10285 (NW973_10285) - 2078923..2080407 (-) 1485 WP_258410764.1 glycoside hydrolase family 32 protein -
  NW973_RS10290 (NW973_10290) - 2080556..2081506 (-) 951 WP_258410765.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=720598 NW973_RS10270 WP_000688498.1 2076882..2077598(+) (agrA) [Staphylococcus aureus strain 03-RR-88]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720598 NW973_RS10270 WP_000688498.1 2076882..2077598(+) (agrA) [Staphylococcus aureus strain 03-RR-88]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996