Detailed information NTG0720561

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW949_RS13245
• Genome accession: NZ_CP102960
• Coordinates: 2668726..2669613 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 07-G-D
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2663726..2674613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW949_RS13215 (NW949_13215)	-	2663754..2663837 (+)	84	WP_031797553.1	hypothetical protein	-
NW949_RS13220 (NW949_13220)	-	2663945..2664442 (-)	498	WP_001065267.1	glutathione peroxidase	-
NW949_RS13225 (NW949_13225)	-	2664452..2664712 (-)	261	WP_001791974.1	hypothetical protein	-
NW949_RS13230 (NW949_13230)	-	2665094..2665207 (-)	114	WP_072384844.1	hypothetical protein	-
NW949_RS13235 (NW949_13235)	-	2665866..2667866 (-)	2001	WP_258415401.1	ABC transporter permease	-
NW949_RS13240 (NW949_13240)	-	2667863..2668618 (-)	756	WP_258415402.1	ABC transporter ATP-binding protein	-
NW949_RS13245 (NW949_13245)	braS	2668726..2669613 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW949_RS13250 (NW949_13250)	braR	2669624..2670289 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW949_RS13255 (NW949_13255)	-	2670315..2670515 (-)	201	WP_000604727.1	hypothetical protein	-
NW949_RS13260 (NW949_13260)	-	2670713..2672137 (+)	1425	WP_258415403.1	alkaline phosphatase	-
NW949_RS13700	-	2672197..2672298 (-)	102	WP_000731976.1	SE2200 family small protein	-
NW949_RS13270 (NW949_13270)	-	2672420..2672875 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW949_RS13275 (NW949_13275)	-	2673120..2673881 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=720561 NW949_RS13245 WP_000143417.1 2668726..2669613(-) (braS) [Staphylococcus aureus strain 07-G-D]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720561 NW949_RS13245 WP_000143417.1 2668726..2669613(-) (braS) [Staphylococcus aureus strain 07-G-D]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99