Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW949_RS09725 Genome accession   NZ_CP102960
Coordinates   2002987..2003703 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 07-G-D     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1997987..2008703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW949_RS09695 (NW949_09695) - 1998203..1998829 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW949_RS09700 (NW949_09700) - 1999190..1999975 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NW949_RS09705 (NW949_09705) - 2000575..2000709 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW949_RS09710 (NW949_09710) agrB 2000945..2001514 (+) 570 WP_258415313.1 accessory gene regulator AgrB -
  NW949_RS09715 (NW949_09715) agrD 2001511..2001651 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NW949_RS09720 (NW949_09720) agrC 2001676..2002968 (+) 1293 WP_064136721.1 quorum-sensing sensor histidine kinase AgrC -
  NW949_RS09725 (NW949_09725) agrA 2002987..2003703 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  NW949_RS09730 (NW949_09730) - 2003775..2003884 (+) 110 Protein_1875 hypothetical protein -
  NW949_RS09735 (NW949_09735) - 2004072..2005031 (-) 960 WP_258415314.1 carbohydrate kinase -
  NW949_RS09740 (NW949_09740) - 2005028..2006512 (-) 1485 WP_103149089.1 sucrose-6-phosphate hydrolase -
  NW949_RS09745 (NW949_09745) - 2006661..2007611 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=720556 NW949_RS09725 WP_000688492.1 2002987..2003703(+) (agrA) [Staphylococcus aureus strain 07-G-D]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720556 NW949_RS09725 WP_000688492.1 2002987..2003703(+) (agrA) [Staphylococcus aureus strain 07-G-D]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1