Detailed information NTG0720555

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW949_RS09320
• Genome accession: NZ_CP102960
• Coordinates: 1924541..1925584 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 07-G-D
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1919541..1930584

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW949_RS09290 (NW949_09290)	-	1919963..1921219 (-)	1257	WP_001793428.1	aminopeptidase	-
NW949_RS09295 (NW949_09295)	-	1921222..1921422 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW949_RS09300 (NW949_09300)	-	1921569..1922033 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW949_RS09305 (NW949_09305)	-	1922040..1922315 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW949_RS09310 (NW949_09310)	-	1922593..1923810 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
NW949_RS09315 (NW949_09315)	vraR	1923922..1924551 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NW949_RS09320 (NW949_09320)	vraS	1924541..1925584 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW949_RS09325 (NW949_09325)	liaF	1925581..1926282 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW949_RS09330 (NW949_09330)	-	1926297..1926683 (-)	387	WP_001110179.1	hypothetical protein	-
NW949_RS09335 (NW949_09335)	map	1926900..1927658 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW949_RS09340 (NW949_09340)	-	1928362..1929348 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW949_RS09345 (NW949_09345)	-	1929838..1930251 (-)	414	WP_001566709.1	hypothetical protein	-
NW949_RS09350 (NW949_09350)	-	1930280..1930391 (-)	112	Protein_1800	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720555 NW949_RS09320 WP_001017131.1 1924541..1925584(-) (vraS) [Staphylococcus aureus strain 07-G-D]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720555 NW949_RS09320 WP_001017131.1 1924541..1925584(-) (vraS) [Staphylococcus aureus strain 07-G-D]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1