Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   PUW57_RS10270 Genome accession   NZ_CP118043
Coordinates   2006634..2008613 (-) Length   659 a.a.
NCBI ID   WP_001054074.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain VSI63     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2001634..2013613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW57_RS10245 (PUW57_10245) recA 2001642..2002781 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  PUW57_RS10250 (PUW57_10250) - 2002855..2004115 (-) 1261 Protein_1948 competence/damage-inducible protein A -
  PUW57_RS10255 (PUW57_10255) - 2004204..2004755 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  PUW57_RS10260 (PUW57_10260) ruvA 2004778..2005368 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA Machinery gene
  PUW57_RS10265 (PUW57_10265) - 2005370..2006602 (-) 1233 WP_000657476.1 MFS transporter -
  PUW57_RS10270 (PUW57_10270) hexB 2006634..2008613 (-) 1980 WP_001054074.1 DNA mismatch repair endonuclease MutL Machinery gene
  PUW57_RS10275 (PUW57_10275) - 2008833..2009036 (+) 204 WP_000191849.1 cold shock domain-containing protein -
  PUW57_RS10280 (PUW57_10280) hexA 2009093..2011669 (-) 2577 WP_001118377.1 DNA mismatch repair protein MutS Machinery gene
  PUW57_RS10285 (PUW57_10285) argR 2011726..2012163 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 73986.20 Da        Isoelectric Point: 5.4718

>NTDB_id=720526 PUW57_RS10270 WP_001054074.1 2006634..2008613(-) (hexB) [Streptococcus agalactiae strain VSI63]
MNLSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHAT
SKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARL
KYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVS
LPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLI
STAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIGADTVSEPIANFTNLDKSDGSVDND
VKNSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYI
IDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEE
VESGIYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADME
KMFKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=720526 PUW57_RS10270 WP_001054074.1 2006634..2008613(-) (hexB) [Streptococcus agalactiae strain VSI63]
ATGAACTTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAG
TAGCGTCGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTC
TTAAAAAGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACA
TCCAAAATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTC
GATTAGTTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTG
AAAAACAGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAACACGCCTGCCAGATTG
AAATACATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGT
TGCTTTTACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTA
TTTATGGTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGT
TTGCCTGAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAA
CCGCTCAATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATC
CTTATCTAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATA
AGCACAGCAATTTCTGAGAGTCTTAAACAATATGACTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCG
AAGTGTAGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGGCTAAAAATGACTTTT
TTATAGGTGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGAT
GTAAAAAACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAA
CTTCATTCATTCTCAGGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTT
CGACTTTTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATT
ATTGATCAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCA
ACAATTGTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAG
ATGTTGGTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAG
GTAGAGTCTGGCATTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTT
GGCTATTATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATC
AGTTAGCGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAG
AAAATGTTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(460-603)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(211-328)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(27-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.892

100

0.689