Detailed information NTG0720479

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW969_RS12675
• Genome accession: NZ_CP102958
• Coordinates: 2609547..2610434 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 15-G-54
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2604547..2615434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW969_RS12645 (NW969_12645)	-	2604575..2604658 (+)	84	WP_031797553.1	hypothetical protein	-
NW969_RS12650 (NW969_12650)	-	2604766..2605263 (-)	498	WP_001065267.1	glutathione peroxidase	-
NW969_RS12655 (NW969_12655)	-	2605273..2605533 (-)	261	WP_001791974.1	hypothetical protein	-
NW969_RS12660 (NW969_12660)	-	2605915..2606028 (-)	114	WP_072384844.1	hypothetical protein	-
NW969_RS12665 (NW969_12665)	-	2606687..2608687 (-)	2001	WP_258411888.1	ABC transporter permease	-
NW969_RS12670 (NW969_12670)	-	2608684..2609439 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NW969_RS12675 (NW969_12675)	braS	2609547..2610434 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW969_RS12680 (NW969_12680)	braR	2610445..2611110 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW969_RS12685 (NW969_12685)	-	2611136..2611336 (-)	201	WP_000604727.1	hypothetical protein	-
NW969_RS12690 (NW969_12690)	-	2611534..2612958 (+)	1425	WP_258412354.1	alkaline phosphatase	-
NW969_RS13185	-	2613018..2613119 (-)	102	WP_000731976.1	SE2200 family small protein	-
NW969_RS12700 (NW969_12700)	-	2613241..2613696 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW969_RS12705 (NW969_12705)	-	2613941..2614702 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=720479 NW969_RS12675 WP_000143419.1 2609547..2610434(-) (braS) [Staphylococcus aureus strain 15-G-54]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720479 NW969_RS12675 WP_000143419.1 2609547..2610434(-) (braS) [Staphylococcus aureus strain 15-G-54]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997