Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW981_RS09730 Genome accession   NZ_CP102956
Coordinates   1999055..1999771 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 26-G-G     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994055..2004771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW981_RS09700 (NW981_09700) - 1994275..1994901 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW981_RS09705 (NW981_09705) - 1995262..1996047 (+) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  NW981_RS09710 (NW981_09710) - 1996644..1996778 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW981_RS09715 (NW981_09715) - 1997014..1997577 (+) 564 WP_001105715.1 accessory gene regulator AgrB -
  NW981_RS09720 (NW981_09720) agrD 1997579..1997719 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  NW981_RS09725 (NW981_09725) agrC 1997744..1999036 (+) 1293 WP_258410127.1 quorum-sensing sensor histidine kinase AgrC -
  NW981_RS09730 (NW981_09730) agrA 1999055..1999771 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  NW981_RS09735 (NW981_09735) - 1999843..1999950 (+) 108 WP_001790167.1 hypothetical protein -
  NW981_RS09740 (NW981_09740) - 2000138..2001097 (-) 960 WP_001253312.1 carbohydrate kinase -
  NW981_RS09745 (NW981_09745) - 2001094..2002578 (-) 1485 WP_258410128.1 sucrose-6-phosphate hydrolase -
  NW981_RS09750 (NW981_09750) - 2002727..2003677 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=720392 NW981_RS09730 WP_000688492.1 1999055..1999771(+) (agrA) [Staphylococcus aureus strain 26-G-G]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720392 NW981_RS09730 WP_000688492.1 1999055..1999771(+) (agrA) [Staphylococcus aureus strain 26-G-G]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1