Detailed information NTG0720391

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW981_RS09340
• Genome accession: NZ_CP102956
• Coordinates: 1920801..1921844 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 26-G-G
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1915801..1926844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW981_RS09310 (NW981_09310)	-	1916222..1917478 (-)	1257	WP_001795108.1	aminopeptidase	-
NW981_RS09315 (NW981_09315)	-	1917481..1917681 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW981_RS09320 (NW981_09320)	-	1917828..1918292 (+)	465	WP_258410110.1	low molecular weight protein-tyrosine-phosphatase	-
NW981_RS09325 (NW981_09325)	-	1918299..1918574 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW981_RS09330 (NW981_09330)	-	1918852..1920069 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
NW981_RS09335 (NW981_09335)	vraR	1920182..1920811 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW981_RS09340 (NW981_09340)	vraS	1920801..1921844 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW981_RS09345 (NW981_09345)	liaF	1921841..1922542 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
NW981_RS09350 (NW981_09350)	-	1922557..1922943 (-)	387	WP_001110179.1	hypothetical protein	-
NW981_RS09355 (NW981_09355)	map	1923160..1923918 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW981_RS09360 (NW981_09360)	-	1924330..1925316 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
NW981_RS09365 (NW981_09365)	-	1925747..1926160 (-)	414	WP_001566709.1	hypothetical protein	-
NW981_RS09370 (NW981_09370)	-	1926189..1926300 (-)	112	Protein_1805	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720391 NW981_RS09340 WP_001017131.1 1920801..1921844(-) (vraS) [Staphylococcus aureus strain 26-G-G]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720391 NW981_RS09340 WP_001017131.1 1920801..1921844(-) (vraS) [Staphylococcus aureus strain 26-G-G]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1