Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW961_RS09910 Genome accession   NZ_CP102955
Coordinates   2023885..2024601 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 28-G-I     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2018885..2029601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW961_RS09880 (NW961_09880) - 2019105..2019731 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW961_RS09885 (NW961_09885) - 2020092..2020877 (+) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  NW961_RS09890 (NW961_09890) - 2021474..2021608 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW961_RS09895 (NW961_09895) - 2021844..2022407 (+) 564 WP_001105715.1 accessory gene regulator AgrB -
  NW961_RS09900 (NW961_09900) agrD 2022409..2022549 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  NW961_RS09905 (NW961_09905) agrC 2022574..2023866 (+) 1293 WP_258411232.1 quorum-sensing sensor histidine kinase AgrC -
  NW961_RS09910 (NW961_09910) agrA 2023885..2024601 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  NW961_RS09915 (NW961_09915) - 2024673..2024780 (+) 108 WP_154284415.1 hypothetical protein -
  NW961_RS09920 (NW961_09920) - 2024968..2025927 (-) 960 WP_001253305.1 carbohydrate kinase -
  NW961_RS09925 (NW961_09925) - 2025924..2027408 (-) 1485 WP_000141430.1 sucrose-6-phosphate hydrolase -
  NW961_RS09930 (NW961_09930) - 2027557..2028507 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=720351 NW961_RS09910 WP_000688492.1 2023885..2024601(+) (agrA) [Staphylococcus aureus strain 28-G-I]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720351 NW961_RS09910 WP_000688492.1 2023885..2024601(+) (agrA) [Staphylococcus aureus strain 28-G-I]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1