Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW951_RS09835 Genome accession   NZ_CP102954
Coordinates   2023523..2024239 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 30-P-10     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2018523..2029239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW951_RS09805 (NW951_09805) - 2018752..2019378 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW951_RS09810 (NW951_09810) - 2019730..2020515 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NW951_RS09815 (NW951_09815) - 2021112..2021246 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW951_RS09820 (NW951_09820) - 2021482..2022045 (+) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  NW951_RS09825 (NW951_09825) agrD 2022048..2022191 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  NW951_RS09830 (NW951_09830) agrC 2022221..2023504 (+) 1284 WP_258413087.1 quorum-sensing sensor histidine kinase AgrC -
  NW951_RS09835 (NW951_09835) agrA 2023523..2024239 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NW951_RS09840 (NW951_09840) - 2024311..2024420 (+) 110 Protein_1897 hypothetical protein -
  NW951_RS09845 (NW951_09845) - 2024608..2025567 (-) 960 WP_001253293.1 carbohydrate kinase -
  NW951_RS09850 (NW951_09850) - 2025564..2027048 (-) 1485 WP_258413088.1 sucrose-6-phosphate hydrolase -
  NW951_RS09855 (NW951_09855) - 2027197..2028147 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=720309 NW951_RS09835 WP_000688498.1 2023523..2024239(+) (agrA) [Staphylococcus aureus strain 30-P-10]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720309 NW951_RS09835 WP_000688498.1 2023523..2024239(+) (agrA) [Staphylococcus aureus strain 30-P-10]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGAAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996