Detailed information NTG0720267

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW977_RS09300
• Genome accession: NZ_CP102953
• Coordinates: 1916024..1917067 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 32-T-13
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1911024..1922067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW977_RS09270 (NW977_09270)	-	1911446..1912702 (-)	1257	WP_001793428.1	aminopeptidase	-
NW977_RS09275 (NW977_09275)	-	1912705..1912905 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW977_RS09280 (NW977_09280)	-	1913052..1913516 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW977_RS09285 (NW977_09285)	-	1913523..1913798 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW977_RS09290 (NW977_09290)	-	1914076..1915293 (+)	1218	WP_179330255.1	YihY/virulence factor BrkB family protein	-
NW977_RS09295 (NW977_09295)	vraR	1915405..1916034 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NW977_RS09300 (NW977_09300)	vraS	1916024..1917067 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW977_RS09305 (NW977_09305)	liaF	1917064..1917765 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW977_RS09310 (NW977_09310)	-	1917780..1918166 (-)	387	WP_258414722.1	hypothetical protein	-
NW977_RS09315 (NW977_09315)	map	1918383..1919141 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW977_RS09320 (NW977_09320)	-	1919672..1920658 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW977_RS09325 (NW977_09325)	-	1921148..1921561 (-)	414	WP_258414837.1	hypothetical protein	-
NW977_RS09330 (NW977_09330)	-	1921590..1921700 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720267 NW977_RS09300 WP_001017131.1 1916024..1917067(-) (vraS) [Staphylococcus aureus strain 32-T-13]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720267 NW977_RS09300 WP_001017131.1 1916024..1917067(-) (vraS) [Staphylococcus aureus strain 32-T-13]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1