Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW967_RS09640 Genome accession   NZ_CP102952
Coordinates   1996452..1997168 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 39-B-49     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1991452..2002168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW967_RS09610 (NW967_09610) - 1991672..1992298 (+) 627 WP_000522384.1 nitroreductase family protein -
  NW967_RS09615 (NW967_09615) - 1992659..1993444 (+) 786 WP_258411231.1 carbon-nitrogen family hydrolase -
  NW967_RS09620 (NW967_09620) - 1994041..1994175 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW967_RS09625 (NW967_09625) - 1994411..1994974 (+) 564 WP_001105715.1 accessory gene regulator AgrB -
  NW967_RS09630 (NW967_09630) agrD 1994976..1995116 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  NW967_RS09635 (NW967_09635) agrC 1995141..1996433 (+) 1293 WP_258411232.1 quorum-sensing sensor histidine kinase AgrC -
  NW967_RS09640 (NW967_09640) agrA 1996452..1997168 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NW967_RS09645 (NW967_09645) - 1997240..1997347 (+) 108 WP_154284415.1 hypothetical protein -
  NW967_RS09650 (NW967_09650) - 1997535..1998494 (-) 960 WP_258411233.1 carbohydrate kinase -
  NW967_RS09655 (NW967_09655) - 1998491..1999975 (-) 1485 WP_258411234.1 sucrose-6-phosphate hydrolase -
  NW967_RS09660 (NW967_09660) - 2000124..2001074 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=720226 NW967_RS09640 WP_000688498.1 1996452..1997168(+) (agrA) [Staphylococcus aureus strain 39-B-49]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720226 NW967_RS09640 WP_000688498.1 1996452..1997168(+) (agrA) [Staphylococcus aureus strain 39-B-49]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996