Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   NW338_RS02450 Genome accession   NZ_CP102945
Coordinates   520343..520912 (+) Length   189 a.a.
NCBI ID   WP_000872881.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SCAID OTT1-2022 (150)     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 515343..525912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW338_RS02425 (NW338_02425) cysE 516556..517203 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  NW338_RS02430 (NW338_02430) cysS 517187..518587 (+) 1401 WP_000631966.1 cysteine--tRNA ligase -
  NW338_RS02435 (NW338_02435) - 518580..518984 (+) 405 WP_000370185.1 Mini-ribonuclease 3 -
  NW338_RS02440 (NW338_02440) rlmB 518992..519738 (+) 747 WP_000390329.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  NW338_RS02445 (NW338_02445) - 519738..520262 (+) 525 WP_000664732.1 NYN domain-containing protein -
  NW338_RS02450 (NW338_02450) sigH 520343..520912 (+) 570 WP_000872881.1 sigma-70 family RNA polymerase sigma factor Regulator
  NW338_RS02455 (NW338_02455) rpmG 521027..521170 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  NW338_RS02460 (NW338_02460) secE 521226..521408 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  NW338_RS02465 (NW338_02465) nusG 521421..521969 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  NW338_RS02470 (NW338_02470) rplK 522150..522572 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  NW338_RS02475 (NW338_02475) rplA 522780..523472 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  NW338_RS02480 (NW338_02480) rplJ 523744..524244 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  NW338_RS02485 (NW338_02485) rplL 524287..524655 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  NW338_RS02490 (NW338_02490) - 524830..525438 (+) 609 WP_000020306.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23096.97 Da        Isoelectric Point: 9.6924

>NTDB_id=720063 NW338_RS02450 WP_000872881.1 520343..520912(+) (sigH) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
MKYDLTTQDSTIKRNNAINDKDFEKLVMNLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=720063 NW338_RS02450 WP_000872881.1 520343..520912(+) (sigH) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
TTGAAATATGATTTGACAACGCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGAATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTTATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979