Detailed information NTG0720063

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: PT798_RS00990
• Genome accession: NZ_CP117979
• Coordinates: 201158..203263 (+)
• Length: 701 a.a.
• NCBI ID: WP_001058990.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain B-41012
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 196158..208263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PT798_RS00970	-	196439..197719 (-)	1281	WP_001180324.1	hydroxymethylglutaryl-CoA reductase, degradative	-
PT798_RS00975	-	197973..199139 (+)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
PT798_RS00980	sey	199361..200026 (-)	666	WP_000644944.1	staphylococcal enterotoxin type Y	-
PT798_RS00985	-	200228..200749 (-)	522	WP_000455986.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
PT798_RS00990	clpE	201158..203263 (+)	2106	WP_001058990.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
PT798_RS00995	-	203325..203495 (-)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
PT798_RS01000	feoB	203508..205502 (-)	1995	WP_000432898.1	ferrous iron transport protein B	-
PT798_RS01005	-	205514..205741 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77839.17 Da
• Isoelectric Point: 4.5825

>NTDB_id=720063 PT798_RS00990 WP_001058990.1 201158..203263(+) (clpE) [Staphylococcus aureus strain B-41012]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGT

Nucleotide

• Length: 2106 bp

>NTDB_id=720063 PT798_RS00990 WP_001058990.1 201158..203263(+) (clpE) [Staphylococcus aureus strain B-41012]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTCCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAAATTTCAATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGCGCTGGGTTTGATGACGGCAACCGTCCAATTGGTAGTTTCC
TATTTGTCGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTTATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTGACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTTATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTTCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCGCGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTACATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.758	91.869	0.448
clpE	Streptococcus pneumoniae Rx1	48.298	88.017	0.425
clpE	Streptococcus pneumoniae D39	48.298	88.017	0.425
clpE	Streptococcus pneumoniae R6	48.298	88.017	0.425
clpE	Streptococcus pneumoniae TIGR4	48.298	88.017	0.425
clpC	Lactococcus lactis subsp. cremoris KW2	46.815	89.586	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.58	93.438	0.417
clpC	Streptococcus thermophilus LMD-9	44.234	90.3	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.3	0.397
clpC	Streptococcus pneumoniae TIGR4	43.851	88.16	0.387
clpC	Streptococcus pneumoniae Rx1	43.851	88.16	0.387
clpC	Streptococcus pneumoniae D39	43.851	88.16	0.387
clpC	Streptococcus mutans UA159	43.577	87.732	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.582	0.382