Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   PBV52_RS27655 Genome accession   NZ_CP117866
Coordinates   6125931..6127055 (-) Length   374 a.a.
NCBI ID   WP_128433552.1    Uniprot ID   -
Organism   Streptomyces sp. T12     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6120931..6132055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PBV52_RS27635 (PBV52_27635) - 6122020..6123516 (+) 1497 WP_274241792.1 sensor histidine kinase -
  PBV52_RS27640 (PBV52_27640) - 6123513..6124169 (+) 657 WP_274241793.1 response regulator transcription factor -
  PBV52_RS27645 (PBV52_27645) - 6124192..6124821 (-) 630 WP_274241794.1 phosphatase PAP2 family protein -
  PBV52_RS27650 (PBV52_27650) - 6125020..6125844 (+) 825 WP_274241796.1 hypothetical protein -
  PBV52_RS27655 (PBV52_27655) disA 6125931..6127055 (-) 1125 WP_128433552.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  PBV52_RS27660 (PBV52_27660) radA 6127137..6128546 (-) 1410 WP_274241798.1 DNA repair protein RadA Machinery gene
  PBV52_RS27665 (PBV52_27665) - 6128729..6130537 (+) 1809 WP_274241800.1 hypothetical protein -
  PBV52_RS27670 (PBV52_27670) - 6130597..6131481 (-) 885 WP_274241801.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40070.79 Da        Isoelectric Point: 4.9201

>NTDB_id=719587 PBV52_RS27655 WP_128433552.1 6125931..6127055(-) (disA) [Streptomyces sp. T12]
MAANDRGAAPGKSGGSAGSDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGFDKTVETMCTGGFVLDVEFAATRLR
ELCKLDGGIVLSSDLSKILRAGVQFVPDATIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALYELDALTHAELLELATVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=719587 PBV52_RS27655 WP_128433552.1 6125931..6127055(-) (disA) [Streptomyces sp. T12]
GTGGCAGCCAACGACCGGGGAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCGGTGGCTCCCGGCACGGCCCTGCGCGACGGACTGGAGCGAGTGCTCCGCGGCAACACCGGCGGGCTCATCGTGC
TCGGCTTCGACAAGACCGTAGAGACGATGTGTACGGGCGGATTCGTCCTGGATGTCGAGTTCGCGGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCGGGCGTGCAGTTCGTGCC
TGACGCGACGATCCCGACGGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TGGTGTCGGTCTCCCAGTCGATGCGGCTCATCGCGCTGTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGAACGTTGTC
AGCACTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCTCCGCGGTCGCCCAGCGACTGGAGATGGTCCGCCGTATCG
CGACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGCCGCCTTCTGGCGCTCCAGCTGGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTCGTGGTGCGCGACTACGTCCCCGAGCCGACGGCCAAGCGTTCCCGCACGGTCGACGA
GGCCCTGTACGAGCTGGACGCCCTCACCCACGCCGAGCTCCTCGAACTTGCCACCGTGGCGAGGGCATTGGGCTACACGG
GATCCCCGGAGGCGCTGGACTCGGCGGTCTCCCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGAGGCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCGGCGAGCGTGGACGACCTGCAGACCGTGGA
CGGCGTGGGCGAGGCCCGGGCGCGGAGCGTGCGGGAGGGGCTGTCGCGACTGGCCGAGAGCTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.821

92.513

0.433