Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NWE25_RS05795 Genome accession   NZ_CP102866
Coordinates   1184236..1184892 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain YS-AT-DS1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1179236..1189892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE25_RS05770 (NWE25_05770) oppF 1179766..1180683 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NWE25_RS05775 (NWE25_05775) - 1180790..1181977 (+) 1188 WP_079891810.1 putative glycoside hydrolase -
  NWE25_RS05780 (NWE25_05780) - 1182095..1182673 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NWE25_RS05785 (NWE25_05785) spx 1182852..1183247 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NWE25_RS05790 (NWE25_05790) - 1183304..1183960 (-) 657 WP_007610610.1 TerC family protein -
  NWE25_RS05795 (NWE25_05795) mecA 1184236..1184892 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NWE25_RS05800 (NWE25_05800) - 1185043..1186203 (+) 1161 WP_038457629.1 competence protein CoiA family protein -
  NWE25_RS05805 (NWE25_05805) pepF 1186431..1188260 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  NWE25_RS05810 (NWE25_05810) - 1188298..1188465 (-) 168 WP_003155026.1 hypothetical protein -
  NWE25_RS05815 (NWE25_05815) spxH 1188751..1189653 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=719408 NWE25_RS05795 WP_003155032.1 1184236..1184892(+) (mecA) [Bacillus velezensis strain YS-AT-DS1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=719408 NWE25_RS05795 WP_003155032.1 1184236..1184892(+) (mecA) [Bacillus velezensis strain YS-AT-DS1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAGTCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895